Varicella-Zoster-Mediated Radiculitis Reactivation following Cervical Spine Surgery: Case Report and Review of the Literature

Varicella-zoster virus and herpes simplex virus types 1 and 2 are neurotropic viruses that can be reactivated after a surgical or stressful intervention. Although such cases are uncommon, consequences can be debilitating, and variable treatment responses merit consideration. We describe a 41-year-ol...

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Main Authors: Doniel Drazin, George Hanna, Faris Shweikeh, Sunil Jeswani, Leah Lovely, Richard Sokolov, John C. Liu
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Infectious Diseases
Online Access:http://dx.doi.org/10.1155/2013/647486
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author Doniel Drazin
George Hanna
Faris Shweikeh
Sunil Jeswani
Leah Lovely
Richard Sokolov
John C. Liu
author_facet Doniel Drazin
George Hanna
Faris Shweikeh
Sunil Jeswani
Leah Lovely
Richard Sokolov
John C. Liu
author_sort Doniel Drazin
collection DOAJ
description Varicella-zoster virus and herpes simplex virus types 1 and 2 are neurotropic viruses that can be reactivated after a surgical or stressful intervention. Although such cases are uncommon, consequences can be debilitating, and variable treatment responses merit consideration. We describe a 41-year-old male with a history of varicella-mediated skin eruptions, who presented with continuing right arm pain, burning, and numbness in a C6 dermatomal distribution following a C5-6 anterior cervical discectomy and fusion and epidural steroid injections. The operative course was uncomplicated and he was discharged home on postoperative day 1. Approximately ten days after surgery, the patient presented to the emergency department complaining of severe pain in his right upper extremity and a vesicular rash from his elbow to his second digit. He was started on Acyclovir and discharged home. On outpatient follow-up, his rash had resolved though his pain continued. The patient was started on a neuromodulating agent for chronic pain. This case adds to the limited literature regarding this rare complication, brings attention to the symptoms for proper diagnosis and treatment, and emphasizes the importance of prompt antiviral therapy. We suggest adding a neuromodulating agent to prevent long-term sequelae and resolve acute symptoms.
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spelling doaj-art-351593cc616d416098c7e3a6b80b75cc2025-02-03T01:23:01ZengWileyCase Reports in Infectious Diseases2090-66252090-66332013-01-01201310.1155/2013/647486647486Varicella-Zoster-Mediated Radiculitis Reactivation following Cervical Spine Surgery: Case Report and Review of the LiteratureDoniel Drazin0George Hanna1Faris Shweikeh2Sunil Jeswani3Leah Lovely4Richard Sokolov5John C. Liu6Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USADepartment of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USADepartment of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USADepartment of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USADepartment of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USADepartment of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USADepartment of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USAVaricella-zoster virus and herpes simplex virus types 1 and 2 are neurotropic viruses that can be reactivated after a surgical or stressful intervention. Although such cases are uncommon, consequences can be debilitating, and variable treatment responses merit consideration. We describe a 41-year-old male with a history of varicella-mediated skin eruptions, who presented with continuing right arm pain, burning, and numbness in a C6 dermatomal distribution following a C5-6 anterior cervical discectomy and fusion and epidural steroid injections. The operative course was uncomplicated and he was discharged home on postoperative day 1. Approximately ten days after surgery, the patient presented to the emergency department complaining of severe pain in his right upper extremity and a vesicular rash from his elbow to his second digit. He was started on Acyclovir and discharged home. On outpatient follow-up, his rash had resolved though his pain continued. The patient was started on a neuromodulating agent for chronic pain. This case adds to the limited literature regarding this rare complication, brings attention to the symptoms for proper diagnosis and treatment, and emphasizes the importance of prompt antiviral therapy. We suggest adding a neuromodulating agent to prevent long-term sequelae and resolve acute symptoms.http://dx.doi.org/10.1155/2013/647486
spellingShingle Doniel Drazin
George Hanna
Faris Shweikeh
Sunil Jeswani
Leah Lovely
Richard Sokolov
John C. Liu
Varicella-Zoster-Mediated Radiculitis Reactivation following Cervical Spine Surgery: Case Report and Review of the Literature
Case Reports in Infectious Diseases
title Varicella-Zoster-Mediated Radiculitis Reactivation following Cervical Spine Surgery: Case Report and Review of the Literature
title_full Varicella-Zoster-Mediated Radiculitis Reactivation following Cervical Spine Surgery: Case Report and Review of the Literature
title_fullStr Varicella-Zoster-Mediated Radiculitis Reactivation following Cervical Spine Surgery: Case Report and Review of the Literature
title_full_unstemmed Varicella-Zoster-Mediated Radiculitis Reactivation following Cervical Spine Surgery: Case Report and Review of the Literature
title_short Varicella-Zoster-Mediated Radiculitis Reactivation following Cervical Spine Surgery: Case Report and Review of the Literature
title_sort varicella zoster mediated radiculitis reactivation following cervical spine surgery case report and review of the literature
url http://dx.doi.org/10.1155/2013/647486
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