Use of Thromboelastogram in Venovenous Extracorporeal Membrane Oxygenation for a Patient with Pulmonary Hemorrhage due to Microscopic Polyangiitis

Systemic heparinisation is required for extracorporeal membrane oxygenation therapy, to prevent clotting of circuit and formation of thrombus in patient. Activated clotting time (ACT) or activated partial thromboplastin time (aPTT) has been the mainstay of monitoring of heparin dose. Thromboelastogr...

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Main Authors: Chak-Kwan Tong, Jun Jin, Qian Du
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Case Reports in Critical Care
Online Access:http://dx.doi.org/10.1155/2019/7241264
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author Chak-Kwan Tong
Jun Jin
Qian Du
author_facet Chak-Kwan Tong
Jun Jin
Qian Du
author_sort Chak-Kwan Tong
collection DOAJ
description Systemic heparinisation is required for extracorporeal membrane oxygenation therapy, to prevent clotting of circuit and formation of thrombus in patient. Activated clotting time (ACT) or activated partial thromboplastin time (aPTT) has been the mainstay of monitoring of heparin dose. Thromboelastogram (TEG) is increasingly being used again in recent years with the advancement in technology. Its clinical usefulness in the monitoring of anticoagulation of ECMO therapy is demonstrated in the case presented. Our patient suffered from severe hemoptysis due to active microscopic polyangiitis and respiratory failure. Heparin infusion was given at the initiation of ECMO support without further aggravation of hemoptysis. Dose of heparin was adjusted successfully with the integration of the clotting profile and TEG results.
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series Case Reports in Critical Care
spelling doaj-art-350be3e297f846c6a86dcb98d0c897162025-02-03T06:08:48ZengWileyCase Reports in Critical Care2090-64202090-64392019-01-01201910.1155/2019/72412647241264Use of Thromboelastogram in Venovenous Extracorporeal Membrane Oxygenation for a Patient with Pulmonary Hemorrhage due to Microscopic PolyangiitisChak-Kwan Tong0Jun Jin1Qian Du2Department of Anaesthesiology, University of Hong Kong, ChinaIntensive Care Unit, University of Hong Kong, Shenzhen Hospital, ChinaIntensive Care Unit, University of Hong Kong, Shenzhen Hospital, ChinaSystemic heparinisation is required for extracorporeal membrane oxygenation therapy, to prevent clotting of circuit and formation of thrombus in patient. Activated clotting time (ACT) or activated partial thromboplastin time (aPTT) has been the mainstay of monitoring of heparin dose. Thromboelastogram (TEG) is increasingly being used again in recent years with the advancement in technology. Its clinical usefulness in the monitoring of anticoagulation of ECMO therapy is demonstrated in the case presented. Our patient suffered from severe hemoptysis due to active microscopic polyangiitis and respiratory failure. Heparin infusion was given at the initiation of ECMO support without further aggravation of hemoptysis. Dose of heparin was adjusted successfully with the integration of the clotting profile and TEG results.http://dx.doi.org/10.1155/2019/7241264
spellingShingle Chak-Kwan Tong
Jun Jin
Qian Du
Use of Thromboelastogram in Venovenous Extracorporeal Membrane Oxygenation for a Patient with Pulmonary Hemorrhage due to Microscopic Polyangiitis
Case Reports in Critical Care
title Use of Thromboelastogram in Venovenous Extracorporeal Membrane Oxygenation for a Patient with Pulmonary Hemorrhage due to Microscopic Polyangiitis
title_full Use of Thromboelastogram in Venovenous Extracorporeal Membrane Oxygenation for a Patient with Pulmonary Hemorrhage due to Microscopic Polyangiitis
title_fullStr Use of Thromboelastogram in Venovenous Extracorporeal Membrane Oxygenation for a Patient with Pulmonary Hemorrhage due to Microscopic Polyangiitis
title_full_unstemmed Use of Thromboelastogram in Venovenous Extracorporeal Membrane Oxygenation for a Patient with Pulmonary Hemorrhage due to Microscopic Polyangiitis
title_short Use of Thromboelastogram in Venovenous Extracorporeal Membrane Oxygenation for a Patient with Pulmonary Hemorrhage due to Microscopic Polyangiitis
title_sort use of thromboelastogram in venovenous extracorporeal membrane oxygenation for a patient with pulmonary hemorrhage due to microscopic polyangiitis
url http://dx.doi.org/10.1155/2019/7241264
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