Los olvidados: Non-BRCA variants associated with Hereditary breast cancer in Mexican population

Los olvidados: Non-BRCA variants associated with Hereditary breast cancer in Mexican population

Abstract Background Hereditary predisposition to breast and ovarian cancer syndrome (HBOC) is a pathological condition with increased cancer risk, including breast (BC), ovarian cancer (OC), and others. HBOC pathogenesis is caused mainly by germline pathogenic variants (GPV) in BRCA1 and BRCA2 genes...

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Main Authors: Dione Aguilar, María Lourdes Garza-Rodríguez, Carolina Elizabeth Muñiz-Garza, Fernando Alcorta Nuñez, Cynthia Mayte Villarreal-Garza, Oscar Vidal-Gutiérrez, Diana Cristina Pérez-Ibave, Carlos Horacio Burciaga-Flores
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Breast Cancer Research
Subjects:
Non-BRCA
Breast cancer
Ovarian cancer
Pathogenic germline variants
Hereditary cancer
Online Access:https://doi.org/10.1186/s13058-024-01957-9
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