Combining Serum DNA Methylation Biomarkers and Protein Tumor Markers Improved Clinical Sensitivity for Early Detection of Colorectal Cancer

Combining Serum DNA Methylation Biomarkers and Protein Tumor Markers Improved Clinical Sensitivity for Early Detection of Colorectal Cancer

Background. Colorectal cancer (CRC) is one of the leading causes of cancer deaths worldwide and in China. Early CRC screening is the best approach to reduce its incidence and mortality rates. The ColoDefense test, a multiplex qPCR assay simultaneously detecting both methylated SEPT9 and SDC2 genes,...

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Bibliographic Details
Main Authors: Guoying Zhang, Fang He, Guodong Zhao, Zihui Huang, Xiang Li, Xia Xia, Yidi Guo, Weiping Xu, Shangmin Xiong, Yong Ma, Minxue Zheng, Wanli Liu
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:International Journal of Genomics
Online Access:http://dx.doi.org/10.1155/2021/6613987
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