Integrated treatment of depression and moderate to severe alcohol use disorder in women shows promise in routine alcohol use disorder care – a pilot study
IntroductionMajor depression and alcohol use disorder affect millions of individuals worldwide and cause significant disability. They often occur together, and their co-occurrence is associated with more negative outcomes than each disorder on its own. Yet, there is a lack of knowledge on how to bes...
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Frontiers Media S.A.
2025-02-01
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| Series: | Frontiers in Psychiatry |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1473988/full |
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| author | Anna Persson Anna Persson Daniel Wallhed Finn Alice Broberg Amanda Westerberg Åsa Magnusson Åsa Magnusson Olof Molander |
| author_facet | Anna Persson Anna Persson Daniel Wallhed Finn Alice Broberg Amanda Westerberg Åsa Magnusson Åsa Magnusson Olof Molander |
| author_sort | Anna Persson |
| collection | DOAJ |
| description | IntroductionMajor depression and alcohol use disorder affect millions of individuals worldwide and cause significant disability. They often occur together, and their co-occurrence is associated with more negative outcomes than each disorder on its own. Yet, there is a lack of knowledge on how to best treat co-occurring depression and alcohol use disorder. A pilot study was conducted to investigate the feasibility, credibility, patient satisfaction, preliminary effect, and potential negative effects of an integrated treatment for depression and alcohol use disorder, which has shown promising results in an earlier pilot trial.MethodsThe study was conducted at an outpatient unit in Stockholm, Sweden. Women (n=7) with current depression and alcohol use disorder were offered integrated group treatment that included evidence-based treatment for depression and alcohol use disorder. Criteria for feasibility were based on an earlier study, treatment credibility was measured using the Credibility/Expectancy Questionnaire and patient satisfaction with the Client Satisfaction Questionnaire.ResultsFeasibility, credibility, and patient satisfaction were high. Depression symptom severity and alcohol consumption decreased from baseline to follow up. Negative effects were reported in terms of increased adverse emotional experiences.DiscussionThe investigated integrated treatment for co-occurring depression and alcohol use disorder continues to show promise. Randomized clinical trials are needed to evaluate its effectiveness. |
| format | Article |
| id | doaj-art-34b5dcda0039422cae52c4a17961563d |
| institution | Kabale University |
| issn | 1664-0640 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Psychiatry |
| spelling | doaj-art-34b5dcda0039422cae52c4a17961563d2025-02-06T11:50:00ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402025-02-011610.3389/fpsyt.2025.14739881473988Integrated treatment of depression and moderate to severe alcohol use disorder in women shows promise in routine alcohol use disorder care – a pilot studyAnna Persson0Anna Persson1Daniel Wallhed Finn2Alice Broberg3Amanda Westerberg4Åsa Magnusson5Åsa Magnusson6Olof Molander7Department of Clinical Neuroscience, Center for Psychiatry Research, Karolinska Institutet, Stockholm, SwedenThe Stockholm Center for Dependency Disorders, Region Stockholm, Stockholm, SwedenWeMind Psychiatry, Stockholm, SwedenWeMind Psychiatry, Stockholm, SwedenWeMind Psychiatry, Stockholm, SwedenDepartment of Clinical Neuroscience, Center for Psychiatry Research, Karolinska Institutet, Stockholm, SwedenThe Stockholm Center for Dependency Disorders, Region Stockholm, Stockholm, SwedenDepartment of Clinical Neuroscience, Center for Psychiatry Research, Karolinska Institutet, Stockholm, SwedenIntroductionMajor depression and alcohol use disorder affect millions of individuals worldwide and cause significant disability. They often occur together, and their co-occurrence is associated with more negative outcomes than each disorder on its own. Yet, there is a lack of knowledge on how to best treat co-occurring depression and alcohol use disorder. A pilot study was conducted to investigate the feasibility, credibility, patient satisfaction, preliminary effect, and potential negative effects of an integrated treatment for depression and alcohol use disorder, which has shown promising results in an earlier pilot trial.MethodsThe study was conducted at an outpatient unit in Stockholm, Sweden. Women (n=7) with current depression and alcohol use disorder were offered integrated group treatment that included evidence-based treatment for depression and alcohol use disorder. Criteria for feasibility were based on an earlier study, treatment credibility was measured using the Credibility/Expectancy Questionnaire and patient satisfaction with the Client Satisfaction Questionnaire.ResultsFeasibility, credibility, and patient satisfaction were high. Depression symptom severity and alcohol consumption decreased from baseline to follow up. Negative effects were reported in terms of increased adverse emotional experiences.DiscussionThe investigated integrated treatment for co-occurring depression and alcohol use disorder continues to show promise. Randomized clinical trials are needed to evaluate its effectiveness.https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1473988/fullmajor depressive disorderalcohol use disorderinvestigational therapiescommunity mental health servicessubstance abuse treatment centers |
| spellingShingle | Anna Persson Anna Persson Daniel Wallhed Finn Alice Broberg Amanda Westerberg Åsa Magnusson Åsa Magnusson Olof Molander Integrated treatment of depression and moderate to severe alcohol use disorder in women shows promise in routine alcohol use disorder care – a pilot study Frontiers in Psychiatry major depressive disorder alcohol use disorder investigational therapies community mental health services substance abuse treatment centers |
| title | Integrated treatment of depression and moderate to severe alcohol use disorder in women shows promise in routine alcohol use disorder care – a pilot study |
| title_full | Integrated treatment of depression and moderate to severe alcohol use disorder in women shows promise in routine alcohol use disorder care – a pilot study |
| title_fullStr | Integrated treatment of depression and moderate to severe alcohol use disorder in women shows promise in routine alcohol use disorder care – a pilot study |
| title_full_unstemmed | Integrated treatment of depression and moderate to severe alcohol use disorder in women shows promise in routine alcohol use disorder care – a pilot study |
| title_short | Integrated treatment of depression and moderate to severe alcohol use disorder in women shows promise in routine alcohol use disorder care – a pilot study |
| title_sort | integrated treatment of depression and moderate to severe alcohol use disorder in women shows promise in routine alcohol use disorder care a pilot study |
| topic | major depressive disorder alcohol use disorder investigational therapies community mental health services substance abuse treatment centers |
| url | https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1473988/full |
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