Re-analysis of the current status of clinical trial registration in China
ObjectiveTo reanalyze and summarize the current status and deficiencies of clinical trial registration in China, based on an analysis of the situation of clinical trial registration in the Chinese Clinical Trial Registry (ChiCTR).MethodsA search was conducted in China National Knowledge Infrastructu...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-01-01
|
| Series: | Frontiers in Medicine |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2024.1394803/full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832576039348338688 |
|---|---|
| author | Shuwen Li Shuwen Li Jianhao Li Wenjing Zeng Zhicheng Li Jietong Zhang Siying Wang Nenggui Xu Zeli Li Zeli Li |
| author_facet | Shuwen Li Shuwen Li Jianhao Li Wenjing Zeng Zhicheng Li Jietong Zhang Siying Wang Nenggui Xu Zeli Li Zeli Li |
| author_sort | Shuwen Li |
| collection | DOAJ |
| description | ObjectiveTo reanalyze and summarize the current status and deficiencies of clinical trial registration in China, based on an analysis of the situation of clinical trial registration in the Chinese Clinical Trial Registry (ChiCTR).MethodsA search was conducted in China National Knowledge Infrastructure (CNKI), Chinese BioMedical Literature Database (CBM), Wangfang Data, VIP Database for Chinese Technical Periodicals (VIP), Web of Science (WoS), PubMed up to December 31, 2023, for literature on the analysis of clinical trial registration based on ChiCTR. NoteExpress software was used for screening, EXCEL for data organization and analysis, the Word Cloud website for constructing word frequency maps, and Origin software for visualization.ResultsAmong the 94 articles included, common analysis items included the number of registered projects, types of research, registration time, types of registration institutions, and regional distribution. Most of the included literature was funded. The publishing institutions involved 20 provinces/municipalities across the country, with hospitals being the majority of the publishing units. Most literature was submitted shortly after search completion and published shortly after submission, with more than half of the articles published in high-quality journals. The total average citation count of the literature was 3.34. The sources of clinical trial registration platforms analyzed in the literature were divided into three categories: single platform, dual platform, and multiple platforms.ConclusionChiCTR plays a key role in enhancing transparency in clinical research, promoting standardization and normalization of research, strengthening domestic and international scientific research cooperation, and advancing medical innovation and public health improvement. However, there are still issues with the quality of registration, focus areas, and the evaluation of registration quality. |
| format | Article |
| id | doaj-art-34a5d132a834482eae83aab6817d7575 |
| institution | Kabale University |
| issn | 2296-858X |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj-art-34a5d132a834482eae83aab6817d75752025-01-31T13:35:05ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2025-01-011110.3389/fmed.2024.13948031394803Re-analysis of the current status of clinical trial registration in ChinaShuwen Li0Shuwen Li1Jianhao Li2Wenjing Zeng3Zhicheng Li4Jietong Zhang5Siying Wang6Nenggui Xu7Zeli Li8Zeli Li9Dongguan Hospital of Guangzhou University of Chinese Medicine, Dongguan Traditional Chinese Medicine Hospital, Dongguan, ChinaClinical Medical College of Acu-Moxi and Rehabilitation, South China Research Center for Acupuncture and Moxibustion, Guangzhou University of Chinese Medicine, Guangzhou, ChinaSchool of Computer, Electronics and Information of Guangxi University, Nanning, ChinaClinical Medical College of Acu-Moxi and Rehabilitation, South China Research Center for Acupuncture and Moxibustion, Guangzhou University of Chinese Medicine, Guangzhou, ChinaClinical Medical College of Acu-Moxi and Rehabilitation, South China Research Center for Acupuncture and Moxibustion, Guangzhou University of Chinese Medicine, Guangzhou, ChinaGuangzhou University of Chinese Medicine, Guangzhou, ChinaGuangzhou University of Chinese Medicine, Guangzhou, ChinaClinical Medical College of Acu-Moxi and Rehabilitation, South China Research Center for Acupuncture and Moxibustion, Guangzhou University of Chinese Medicine, Guangzhou, ChinaDongguan Hospital of Guangzhou University of Chinese Medicine, Dongguan Traditional Chinese Medicine Hospital, Dongguan, ChinaClinical Medical College of Acu-Moxi and Rehabilitation, South China Research Center for Acupuncture and Moxibustion, Guangzhou University of Chinese Medicine, Guangzhou, ChinaObjectiveTo reanalyze and summarize the current status and deficiencies of clinical trial registration in China, based on an analysis of the situation of clinical trial registration in the Chinese Clinical Trial Registry (ChiCTR).MethodsA search was conducted in China National Knowledge Infrastructure (CNKI), Chinese BioMedical Literature Database (CBM), Wangfang Data, VIP Database for Chinese Technical Periodicals (VIP), Web of Science (WoS), PubMed up to December 31, 2023, for literature on the analysis of clinical trial registration based on ChiCTR. NoteExpress software was used for screening, EXCEL for data organization and analysis, the Word Cloud website for constructing word frequency maps, and Origin software for visualization.ResultsAmong the 94 articles included, common analysis items included the number of registered projects, types of research, registration time, types of registration institutions, and regional distribution. Most of the included literature was funded. The publishing institutions involved 20 provinces/municipalities across the country, with hospitals being the majority of the publishing units. Most literature was submitted shortly after search completion and published shortly after submission, with more than half of the articles published in high-quality journals. The total average citation count of the literature was 3.34. The sources of clinical trial registration platforms analyzed in the literature were divided into three categories: single platform, dual platform, and multiple platforms.ConclusionChiCTR plays a key role in enhancing transparency in clinical research, promoting standardization and normalization of research, strengthening domestic and international scientific research cooperation, and advancing medical innovation and public health improvement. However, there are still issues with the quality of registration, focus areas, and the evaluation of registration quality.https://www.frontiersin.org/articles/10.3389/fmed.2024.1394803/fullcurrent state of registrationChinese clinical trial registryevaluation of registration qualityre-analysisinsufficiency |
| spellingShingle | Shuwen Li Shuwen Li Jianhao Li Wenjing Zeng Zhicheng Li Jietong Zhang Siying Wang Nenggui Xu Zeli Li Zeli Li Re-analysis of the current status of clinical trial registration in China Frontiers in Medicine current state of registration Chinese clinical trial registry evaluation of registration quality re-analysis insufficiency |
| title | Re-analysis of the current status of clinical trial registration in China |
| title_full | Re-analysis of the current status of clinical trial registration in China |
| title_fullStr | Re-analysis of the current status of clinical trial registration in China |
| title_full_unstemmed | Re-analysis of the current status of clinical trial registration in China |
| title_short | Re-analysis of the current status of clinical trial registration in China |
| title_sort | re analysis of the current status of clinical trial registration in china |
| topic | current state of registration Chinese clinical trial registry evaluation of registration quality re-analysis insufficiency |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2024.1394803/full |
| work_keys_str_mv | AT shuwenli reanalysisofthecurrentstatusofclinicaltrialregistrationinchina AT shuwenli reanalysisofthecurrentstatusofclinicaltrialregistrationinchina AT jianhaoli reanalysisofthecurrentstatusofclinicaltrialregistrationinchina AT wenjingzeng reanalysisofthecurrentstatusofclinicaltrialregistrationinchina AT zhichengli reanalysisofthecurrentstatusofclinicaltrialregistrationinchina AT jietongzhang reanalysisofthecurrentstatusofclinicaltrialregistrationinchina AT siyingwang reanalysisofthecurrentstatusofclinicaltrialregistrationinchina AT nengguixu reanalysisofthecurrentstatusofclinicaltrialregistrationinchina AT zelili reanalysisofthecurrentstatusofclinicaltrialregistrationinchina AT zelili reanalysisofthecurrentstatusofclinicaltrialregistrationinchina |