Dynamic Monitoring of Circulating Tumor DNA to Predict the Risk of Non In Situ Recurrence of Postoperative Glioma: A Prospective Cohort Study

Dynamic Monitoring of Circulating Tumor DNA to Predict the Risk of Non In Situ Recurrence of Postoperative Glioma: A Prospective Cohort Study

ABSTRACT Background Glioma recurrence can be divided into in situ recurrence and non‐in situ recurrence, and the mutation evolution of gliomas with different recurrence patterns is still unknown. We used sequential sequencing of circulating tumor DNA (ctDNA) to compare the somatic mutation profile a...

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Main Authors: Guangzhong Guo, Ziyue Zhang, Jiubing Zhang, Dayang Wang, Sensen Xu, Shuang Wu, Kaiyuan Deng, Yage Bu, Zhiyuan Sheng, Jinliang Yu, Yushuai Gao, Zhaoyue Yan, Ruijiao Zhao, Meiyun Wang, Tianxiao Li, Xingyao Bu
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:Cancer Medicine
Subjects:
biomarker
circulating tumor DNA
clonal evolution
glioma
risk stratification
tumor recurrence
Online Access:https://doi.org/10.1002/cam4.70733
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