Familial Recurrence of Cerebral Palsy with Multiple Risk Factors
The recurrence of cerebral palsy in the same family is uncommon. We, however, report on two families with two or more affected siblings. In both families, numerous potential risk factors were identified including environmental, obstetric, and possible maternal effects. We hypothesize that multiple r...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Case Reports in Pediatrics |
| Online Access: | http://dx.doi.org/10.1155/2011/307857 |
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| _version_ | 1832562724583768064 |
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| author | Lawrence P. Richer Nancy A. Dower Norma Leonard Alicia K. J. Chan Charlene M. T. Robertson |
| author_facet | Lawrence P. Richer Nancy A. Dower Norma Leonard Alicia K. J. Chan Charlene M. T. Robertson |
| author_sort | Lawrence P. Richer |
| collection | DOAJ |
| description | The recurrence of cerebral palsy in the same family is uncommon. We, however, report on two families with two or more affected siblings. In both families, numerous potential risk factors were identified including environmental, obstetric, and possible maternal effects. We hypothesize that multiple risk factors may lead to the increased risk of recurrence of cerebral palsy in families. Intrinsic and maternal risk factors should be investigated in all cases of cerebral palsy to properly counsel families on the risk of recurrence. Recent studies of genetic polymorphisms associated with cerebral palsy are considered with reference to our observations in these two families. |
| format | Article |
| id | doaj-art-34751289669845cb8473aacef9f75bb2 |
| institution | Kabale University |
| issn | 2090-6803 2090-6811 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pediatrics |
| spelling | doaj-art-34751289669845cb8473aacef9f75bb22025-02-03T01:21:51ZengWileyCase Reports in Pediatrics2090-68032090-68112011-01-01201110.1155/2011/307857307857Familial Recurrence of Cerebral Palsy with Multiple Risk FactorsLawrence P. Richer0Nancy A. Dower1Norma Leonard2Alicia K. J. Chan3Charlene M. T. Robertson4Division of Neurology, Department of Pediatrics, University of Alberta, 4-588 Edmonton Clinic Health Academy (ECHA), Edmonton, AB, T6G 1C9, CanadaDivision of Hematology, Department of Pediatrics, University of Alberta, Edmonton, AB, T6G 1C9, CanadaDepartment of Medical Genetics, University of Alberta, Edmonton, AB, T6G 2H7, CanadaDepartment of Medical Genetics, University of Alberta, Edmonton, AB, T6G 2H7, CanadaDivision of Neurodevelopmental Pediatrics and Rehabilitative Medicine, Department of Pediatrics, University of Alberta, Edmonton, AB, T6G 0B7, CanadaThe recurrence of cerebral palsy in the same family is uncommon. We, however, report on two families with two or more affected siblings. In both families, numerous potential risk factors were identified including environmental, obstetric, and possible maternal effects. We hypothesize that multiple risk factors may lead to the increased risk of recurrence of cerebral palsy in families. Intrinsic and maternal risk factors should be investigated in all cases of cerebral palsy to properly counsel families on the risk of recurrence. Recent studies of genetic polymorphisms associated with cerebral palsy are considered with reference to our observations in these two families.http://dx.doi.org/10.1155/2011/307857 |
| spellingShingle | Lawrence P. Richer Nancy A. Dower Norma Leonard Alicia K. J. Chan Charlene M. T. Robertson Familial Recurrence of Cerebral Palsy with Multiple Risk Factors Case Reports in Pediatrics |
| title | Familial Recurrence of Cerebral Palsy with Multiple Risk Factors |
| title_full | Familial Recurrence of Cerebral Palsy with Multiple Risk Factors |
| title_fullStr | Familial Recurrence of Cerebral Palsy with Multiple Risk Factors |
| title_full_unstemmed | Familial Recurrence of Cerebral Palsy with Multiple Risk Factors |
| title_short | Familial Recurrence of Cerebral Palsy with Multiple Risk Factors |
| title_sort | familial recurrence of cerebral palsy with multiple risk factors |
| url | http://dx.doi.org/10.1155/2011/307857 |
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