Non-small cell lung cancer and the tumor microenvironment: making headway from targeted therapies to advanced immunotherapy

Non-small cell lung cancer and the tumor microenvironment: making headway from targeted therapies to advanced immunotherapy

Over the past decades, significant progress has been made in the understanding of non-small cell lung cancer (NSCLC) biology and tumor progression mechanisms, resulting in the development of novel strategies for early detection and wide-ranging care approaches. Since their introduction, over 20 year...

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Main Authors: Anna De Lucia, Lucia Mazzotti, Anna Gaimari, Matteo Zurlo, Roberta Maltoni, Claudio Cerchione, Sara Bravaccini, Angelo Delmonte, Lucio Crinò, Patricia Borges de Souza, Luigi Pasini, Fabio Nicolini, Fabrizio Bianchi, Manel Juan, Hugo Calderon, Chiara Magnoni, Luca Gazzola, Paola Ulivi, Massimiliano Mazza
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Immunology
Subjects:
non-small cell lung cancer (NSCLC)
tumor microenvironment (TME)
tyrosine kinase inhibitors (TKIs)
immune checkpoint inhibitors (ICIs)
chimeric antigen receptor (CAR) T cell therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1515748/full
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