Impact of pharmacist-led medication review among hemodialysis patients: a systematic review
Background Medication-related problems (DRPs) are common among hemodialysis (HD) patients, and pharmacist-led medication reviews have been shown to address such issues. However, the impact of these interventions and the specific types of DRPs among this patient group remain unclear.Objectives This s...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2025-12-01
|
| Series: | Journal of Pharmaceutical Policy and Practice |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/20523211.2024.2446912 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832540789302886400 |
|---|---|
| author | Ganesh Sritheran Paneerselvam Chen Kah Yee Muhammad Junaid Farrukh Ana Yuda Andi Hermansyah Mohd. Fadli Mohd. Asmani Ibrahim Abdullah Long Chiau Ming |
| author_facet | Ganesh Sritheran Paneerselvam Chen Kah Yee Muhammad Junaid Farrukh Ana Yuda Andi Hermansyah Mohd. Fadli Mohd. Asmani Ibrahim Abdullah Long Chiau Ming |
| author_sort | Ganesh Sritheran Paneerselvam |
| collection | DOAJ |
| description | Background Medication-related problems (DRPs) are common among hemodialysis (HD) patients, and pharmacist-led medication reviews have been shown to address such issues. However, the impact of these interventions and the specific types of DRPs among this patient group remain unclear.Objectives This systematic review aimed to assess the impact of pharmacist-led medication reviews among HD patients, identify the most prevalent types of DRPs, and explore the factors associated with these problems.Methods A systematic search was conducted across databases such as Medline via PubMed, Science Direct, Google Scholar, and EBSCOHost, for studies published from January 2012 to July 2023. Studies included were those focusing on pharmacist interventions in HD patients. The Newcastle-Ottawa Scale (NOS) was used to evaluate the quality of selected studies.Results After screening 343 articles, 10 studies (involving 1342 HD patients) were included. Nine studies were rated as high quality, and one as fair quality. The studies predominantly used prospective designs. A total of 4511 DRPs were identified, with suboptimal drug treatment, non-adherence to medications, and drug use without indication being the most common issues. Pharmacist interventions led to the resolution or reduction of DRPs, shorter hospital stays, improvement in laboratory outcomes, better quality of life (QoL), and enhanced patient understanding. However, interventions had minimal or no significant impact on reducing unplanned admissions, mortality rates, or improving medication adherence. The reduction in healthcare utilisation costs was inconsistent across studies.Conclusion Pharmacist-led medication reviews were effective in resolving DRPs and improving clinical outcomes in HD patients, such as quality of life and lab values. However, their impact on healthcare utilisation and mortality remains inconclusive. Further research with longer follow-up is needed to assess the long-term economic outcomes of these interventions. |
| format | Article |
| id | doaj-art-346092a9daa64720b582f5f980579de2 |
| institution | Kabale University |
| issn | 2052-3211 |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Journal of Pharmaceutical Policy and Practice |
| spelling | doaj-art-346092a9daa64720b582f5f980579de22025-02-04T15:25:08ZengTaylor & Francis GroupJournal of Pharmaceutical Policy and Practice2052-32112025-12-0118110.1080/20523211.2024.2446912Impact of pharmacist-led medication review among hemodialysis patients: a systematic reviewGanesh Sritheran Paneerselvam0Chen Kah Yee1Muhammad Junaid Farrukh2Ana Yuda3Andi Hermansyah4Mohd. Fadli Mohd. Asmani5Ibrahim Abdullah6Long Chiau Ming7School of Pharmacy, Taylor’s University, Subang Jaya, MalaysiaSchool of Pharmacy, Taylor’s University, Subang Jaya, MalaysiaFaculty of Pharmaceutical Sciences, UCSI University, Kuala Lumpur, MalaysiaDepartment of Pharmacy Practice, Faculty of Pharmacy, Universitas Airlangga, Surabaya, IndonesiaDepartment of Pharmacy Practice, Faculty of Pharmacy, Universitas Airlangga, Surabaya, IndonesiaSchool of Pharmacy, Management and Science University, Shah Alam, MalaysiaSchool of Pharmacy, Management and Science University, Shah Alam, MalaysiaDepartment of Pharmacy Practice, Faculty of Pharmacy, Universitas Airlangga, Surabaya, IndonesiaBackground Medication-related problems (DRPs) are common among hemodialysis (HD) patients, and pharmacist-led medication reviews have been shown to address such issues. However, the impact of these interventions and the specific types of DRPs among this patient group remain unclear.Objectives This systematic review aimed to assess the impact of pharmacist-led medication reviews among HD patients, identify the most prevalent types of DRPs, and explore the factors associated with these problems.Methods A systematic search was conducted across databases such as Medline via PubMed, Science Direct, Google Scholar, and EBSCOHost, for studies published from January 2012 to July 2023. Studies included were those focusing on pharmacist interventions in HD patients. The Newcastle-Ottawa Scale (NOS) was used to evaluate the quality of selected studies.Results After screening 343 articles, 10 studies (involving 1342 HD patients) were included. Nine studies were rated as high quality, and one as fair quality. The studies predominantly used prospective designs. A total of 4511 DRPs were identified, with suboptimal drug treatment, non-adherence to medications, and drug use without indication being the most common issues. Pharmacist interventions led to the resolution or reduction of DRPs, shorter hospital stays, improvement in laboratory outcomes, better quality of life (QoL), and enhanced patient understanding. However, interventions had minimal or no significant impact on reducing unplanned admissions, mortality rates, or improving medication adherence. The reduction in healthcare utilisation costs was inconsistent across studies.Conclusion Pharmacist-led medication reviews were effective in resolving DRPs and improving clinical outcomes in HD patients, such as quality of life and lab values. However, their impact on healthcare utilisation and mortality remains inconclusive. Further research with longer follow-up is needed to assess the long-term economic outcomes of these interventions.https://www.tandfonline.com/doi/10.1080/20523211.2024.2446912Non-communicable diseasedrug safetydisease burdenrenal diseasehemodialysispatient safety |
| spellingShingle | Ganesh Sritheran Paneerselvam Chen Kah Yee Muhammad Junaid Farrukh Ana Yuda Andi Hermansyah Mohd. Fadli Mohd. Asmani Ibrahim Abdullah Long Chiau Ming Impact of pharmacist-led medication review among hemodialysis patients: a systematic review Journal of Pharmaceutical Policy and Practice Non-communicable disease drug safety disease burden renal disease hemodialysis patient safety |
| title | Impact of pharmacist-led medication review among hemodialysis patients: a systematic review |
| title_full | Impact of pharmacist-led medication review among hemodialysis patients: a systematic review |
| title_fullStr | Impact of pharmacist-led medication review among hemodialysis patients: a systematic review |
| title_full_unstemmed | Impact of pharmacist-led medication review among hemodialysis patients: a systematic review |
| title_short | Impact of pharmacist-led medication review among hemodialysis patients: a systematic review |
| title_sort | impact of pharmacist led medication review among hemodialysis patients a systematic review |
| topic | Non-communicable disease drug safety disease burden renal disease hemodialysis patient safety |
| url | https://www.tandfonline.com/doi/10.1080/20523211.2024.2446912 |
| work_keys_str_mv | AT ganeshsritheranpaneerselvam impactofpharmacistledmedicationreviewamonghemodialysispatientsasystematicreview AT chenkahyee impactofpharmacistledmedicationreviewamonghemodialysispatientsasystematicreview AT muhammadjunaidfarrukh impactofpharmacistledmedicationreviewamonghemodialysispatientsasystematicreview AT anayuda impactofpharmacistledmedicationreviewamonghemodialysispatientsasystematicreview AT andihermansyah impactofpharmacistledmedicationreviewamonghemodialysispatientsasystematicreview AT mohdfadlimohdasmani impactofpharmacistledmedicationreviewamonghemodialysispatientsasystematicreview AT ibrahimabdullah impactofpharmacistledmedicationreviewamonghemodialysispatientsasystematicreview AT longchiauming impactofpharmacistledmedicationreviewamonghemodialysispatientsasystematicreview |