Prematurity and Related Biochemical Outcomes: Study of Bone Mineralization and Renal Function Parameters in Preterm Infants

Preterm is defined as a baby with a gestation of less than 37 completed weeks. In this study, serum calcium, phosphorus, ALP, creatinine, and electrolytes were measured in preterm babies. The present study comprised of 75 preterm babies of which 25 were of 28–30 weeks, 25 were of 30–32 weeks, and re...

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Main Authors: Sarika Singh Chauhan, Purnima Dey Sarkar, Bhawna Bhimte
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Biochemistry Research International
Online Access:http://dx.doi.org/10.1155/2011/740370
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author Sarika Singh Chauhan
Purnima Dey Sarkar
Bhawna Bhimte
author_facet Sarika Singh Chauhan
Purnima Dey Sarkar
Bhawna Bhimte
author_sort Sarika Singh Chauhan
collection DOAJ
description Preterm is defined as a baby with a gestation of less than 37 completed weeks. In this study, serum calcium, phosphorus, ALP, creatinine, and electrolytes were measured in preterm babies. The present study comprised of 75 preterm babies of which 25 were of 28–30 weeks, 25 were of 30–32 weeks, and remaining 25 were of 34–36 weeks (controls) of gestational age. Serum calcium and phosphorus levels were found to be significantly decreased, and serum ALP, creatinine, and electrolytes were found to be significantly increased (𝑃<0.001) at 28–30 weeks as compared to controls, but serum calcium and phosphorous levels were found to be insignificantly decreased, whereas serum ALP activities were found to be insignificantly increased at 28–30 weeks as compared to 30–32 weeks of gestational age in preterm babies. It can be concluded that high serum ALP activity and low serum calcium and phosphorus levels are associated with preterm babies. A significant difference in the mean values of these renal function parameters was also obtained, except for serum sodium and potassium.
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spelling doaj-art-34555042821c456bbcb4a7770624f1c92025-02-03T06:07:18ZengWileyBiochemistry Research International2090-22472090-22552011-01-01201110.1155/2011/740370740370Prematurity and Related Biochemical Outcomes: Study of Bone Mineralization and Renal Function Parameters in Preterm InfantsSarika Singh Chauhan0Purnima Dey Sarkar1Bhawna Bhimte2Department of Biochemistry, Mahatma Gandhi Medical College, Indore, IndiaDepartment of Biochemistry, Mahatma Gandhi Medical College, Indore, IndiaDepartment of Biochemistry, Mahatma Gandhi Medical College, Indore, IndiaPreterm is defined as a baby with a gestation of less than 37 completed weeks. In this study, serum calcium, phosphorus, ALP, creatinine, and electrolytes were measured in preterm babies. The present study comprised of 75 preterm babies of which 25 were of 28–30 weeks, 25 were of 30–32 weeks, and remaining 25 were of 34–36 weeks (controls) of gestational age. Serum calcium and phosphorus levels were found to be significantly decreased, and serum ALP, creatinine, and electrolytes were found to be significantly increased (𝑃<0.001) at 28–30 weeks as compared to controls, but serum calcium and phosphorous levels were found to be insignificantly decreased, whereas serum ALP activities were found to be insignificantly increased at 28–30 weeks as compared to 30–32 weeks of gestational age in preterm babies. It can be concluded that high serum ALP activity and low serum calcium and phosphorus levels are associated with preterm babies. A significant difference in the mean values of these renal function parameters was also obtained, except for serum sodium and potassium.http://dx.doi.org/10.1155/2011/740370
spellingShingle Sarika Singh Chauhan
Purnima Dey Sarkar
Bhawna Bhimte
Prematurity and Related Biochemical Outcomes: Study of Bone Mineralization and Renal Function Parameters in Preterm Infants
Biochemistry Research International
title Prematurity and Related Biochemical Outcomes: Study of Bone Mineralization and Renal Function Parameters in Preterm Infants
title_full Prematurity and Related Biochemical Outcomes: Study of Bone Mineralization and Renal Function Parameters in Preterm Infants
title_fullStr Prematurity and Related Biochemical Outcomes: Study of Bone Mineralization and Renal Function Parameters in Preterm Infants
title_full_unstemmed Prematurity and Related Biochemical Outcomes: Study of Bone Mineralization and Renal Function Parameters in Preterm Infants
title_short Prematurity and Related Biochemical Outcomes: Study of Bone Mineralization and Renal Function Parameters in Preterm Infants
title_sort prematurity and related biochemical outcomes study of bone mineralization and renal function parameters in preterm infants
url http://dx.doi.org/10.1155/2011/740370
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