Double-Expressor Appendiceal Burkitt’s Lymphoma: A Case Report and Literature Review

Background. Appendiceal lymphoma is a very rare entity accounting for 0.015% of all gastrointestinal lymphoma cases. Acute appendicitis is the most common presentation of primary appendix neoplasms. Burkitt’s lymphoma presenting as an acute appendicitis is a rare entity with around 21% of the cases...

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Main Authors: Osama N. Dukmak, Hamzeh M. I. Abugharbieh, Mohammad Farid Emar, Iman Khamayseh, Salem M. Tos, Rafiq Salhab
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Case Reports in Hematology
Online Access:http://dx.doi.org/10.1155/2022/6795699
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author Osama N. Dukmak
Hamzeh M. I. Abugharbieh
Mohammad Farid Emar
Iman Khamayseh
Salem M. Tos
Rafiq Salhab
author_facet Osama N. Dukmak
Hamzeh M. I. Abugharbieh
Mohammad Farid Emar
Iman Khamayseh
Salem M. Tos
Rafiq Salhab
author_sort Osama N. Dukmak
collection DOAJ
description Background. Appendiceal lymphoma is a very rare entity accounting for 0.015% of all gastrointestinal lymphoma cases. Acute appendicitis is the most common presentation of primary appendix neoplasms. Burkitt’s lymphoma presenting as an acute appendicitis is a rare entity with around 21% of the cases presenting as a lower iliac fossa mass. Case Presentation. A 23-year-old male was admitted to the surgical ward as a case of acute appendicitis with localized tenderness in the right iliac fossa, positive rebound tenderness, a positive Rovsing’s sign, and ultrasound findings of suspected complicated appendicitis. Appendectomy was performed. Histopathological examination of the appendectomy specimen revealed a double-expressor non-Hodgkin diffuse large cell lymphoma with Burkitt’s-like morphology. He was sent for chemotherapy treatment. Conclusion. Only 34 cases of Burkitt’s lymphoma have been reported to present as acute appendicitis. Histological examination following appendectomy for an apparent appendicitis is essential. Furthermore, complete blood count and a computed tomography scan aid the diagnosis of lymphoma. Double-expressor lymphoma has been shown to have poor outcomes. Therefore, prompt and aggressive treatment is vital.
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spelling doaj-art-344ee0a1c9c246608f4c4dbea0eadcf82025-02-03T01:12:21ZengWileyCase Reports in Hematology2090-65792022-01-01202210.1155/2022/6795699Double-Expressor Appendiceal Burkitt’s Lymphoma: A Case Report and Literature ReviewOsama N. Dukmak0Hamzeh M. I. Abugharbieh1Mohammad Farid Emar2Iman Khamayseh3Salem M. Tos4Rafiq Salhab5Al-Quds UniversityAl-Quds UniversityAl-Ahli HospitalAl-Quds UniversityAl-Quds UniversityAl-Ahli HospitalBackground. Appendiceal lymphoma is a very rare entity accounting for 0.015% of all gastrointestinal lymphoma cases. Acute appendicitis is the most common presentation of primary appendix neoplasms. Burkitt’s lymphoma presenting as an acute appendicitis is a rare entity with around 21% of the cases presenting as a lower iliac fossa mass. Case Presentation. A 23-year-old male was admitted to the surgical ward as a case of acute appendicitis with localized tenderness in the right iliac fossa, positive rebound tenderness, a positive Rovsing’s sign, and ultrasound findings of suspected complicated appendicitis. Appendectomy was performed. Histopathological examination of the appendectomy specimen revealed a double-expressor non-Hodgkin diffuse large cell lymphoma with Burkitt’s-like morphology. He was sent for chemotherapy treatment. Conclusion. Only 34 cases of Burkitt’s lymphoma have been reported to present as acute appendicitis. Histological examination following appendectomy for an apparent appendicitis is essential. Furthermore, complete blood count and a computed tomography scan aid the diagnosis of lymphoma. Double-expressor lymphoma has been shown to have poor outcomes. Therefore, prompt and aggressive treatment is vital.http://dx.doi.org/10.1155/2022/6795699
spellingShingle Osama N. Dukmak
Hamzeh M. I. Abugharbieh
Mohammad Farid Emar
Iman Khamayseh
Salem M. Tos
Rafiq Salhab
Double-Expressor Appendiceal Burkitt’s Lymphoma: A Case Report and Literature Review
Case Reports in Hematology
title Double-Expressor Appendiceal Burkitt’s Lymphoma: A Case Report and Literature Review
title_full Double-Expressor Appendiceal Burkitt’s Lymphoma: A Case Report and Literature Review
title_fullStr Double-Expressor Appendiceal Burkitt’s Lymphoma: A Case Report and Literature Review
title_full_unstemmed Double-Expressor Appendiceal Burkitt’s Lymphoma: A Case Report and Literature Review
title_short Double-Expressor Appendiceal Burkitt’s Lymphoma: A Case Report and Literature Review
title_sort double expressor appendiceal burkitt s lymphoma a case report and literature review
url http://dx.doi.org/10.1155/2022/6795699
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