Impact of point‐of‐care maternal viral load testing at delivery on vertical HIV transmission risk assessment and neonatal prophylaxis: a cluster randomized trial

Impact of point‐of‐care maternal viral load testing at delivery on vertical HIV transmission risk assessment and neonatal prophylaxis: a cluster randomized trial

Abstract Introduction Despite global reductions in vertical HIV transmission (VHT), 120,000 children newly acquired HIV in 2023. High maternal viral load (VL) is a major risk factor for VHT. We estimated the impact of point‐of‐care (PoC) maternal VL testing at delivery in profiling the risk of VHT a...

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Main Authors: Anange Fred Lwilla, Kira Elsbernd, Siriel Boniface, Raphael Edom, Arlete Mahumane, Bindiya Meggi, W. Chris Buck, Joaquim Lequechane, Kassia Pereira, Nhamo Chiwerengo, Falume Chale, Chishamiso Mudenyanga, Dadirayi Mutsaka, Marianna Mueller, Nyanda E. Ntinginya, Nuno Taveira, Michael Hoelscher, Ilesh Jani, Arne Kroidl, Issa Sabi, and the LIFE Study Consortium
Format: Article
Language:English
Published: Wiley 2025-08-01
Series:Journal of the International AIDS Society
Subjects:
HIV acquisitions
infant
newborn
point‐of‐care systems
risk assessment
viral load
Online Access:https://doi.org/10.1002/jia2.70021
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https://doi.org/10.1002/jia2.70021

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