Rivaroxaban: Expanded Role in Cardiovascular Disease Management—A Literature Review

Direct oral anticoagulants (DOACs) are widely used for the prevention of stroke in nonvalvular atrial fibrillation, treatment of deep venous thrombosis and pulmonary embolism, and as prophylaxis after hip and knee surgery after approval by the Food and Drug Administration. In the last decade, DOACs...

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Main Authors: Muhammad Ajmal, Jacob Friedman, Qurat Ul Ain Riaz Sipra, Tom Lassar
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Cardiovascular Therapeutics
Online Access:http://dx.doi.org/10.1155/2021/8886210
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author Muhammad Ajmal
Jacob Friedman
Qurat Ul Ain Riaz Sipra
Tom Lassar
author_facet Muhammad Ajmal
Jacob Friedman
Qurat Ul Ain Riaz Sipra
Tom Lassar
author_sort Muhammad Ajmal
collection DOAJ
description Direct oral anticoagulants (DOACs) are widely used for the prevention of stroke in nonvalvular atrial fibrillation, treatment of deep venous thrombosis and pulmonary embolism, and as prophylaxis after hip and knee surgery after approval by the Food and Drug Administration. In the last decade, DOACs were studied for various indications; this review is focused on rivaroxaban, a factor Xa inhibitor, which is used in an expanded evidence-based fashion for coronary artery disease, peripheral artery disease, heart failure, malignancy, and prophylaxis of deep venous thrombosis in acute medical illnesses.
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institution Kabale University
issn 1755-5914
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language English
publishDate 2021-01-01
publisher Wiley
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series Cardiovascular Therapeutics
spelling doaj-art-342b2726d45a4c379fbea2f14c951dac2025-02-03T01:05:05ZengWileyCardiovascular Therapeutics1755-59141755-59222021-01-01202110.1155/2021/88862108886210Rivaroxaban: Expanded Role in Cardiovascular Disease Management—A Literature ReviewMuhammad Ajmal0Jacob Friedman1Qurat Ul Ain Riaz Sipra2Tom Lassar3University of Arizona, College of Medicine, Tucson, AZ, USAUniversity of Arizona, College of Medicine, Tucson, AZ, USAUniversity of Arizona, College of Medicine, Tucson, AZ, USAUniversity of Arizona, College of Medicine, Tucson, AZ, USADirect oral anticoagulants (DOACs) are widely used for the prevention of stroke in nonvalvular atrial fibrillation, treatment of deep venous thrombosis and pulmonary embolism, and as prophylaxis after hip and knee surgery after approval by the Food and Drug Administration. In the last decade, DOACs were studied for various indications; this review is focused on rivaroxaban, a factor Xa inhibitor, which is used in an expanded evidence-based fashion for coronary artery disease, peripheral artery disease, heart failure, malignancy, and prophylaxis of deep venous thrombosis in acute medical illnesses.http://dx.doi.org/10.1155/2021/8886210
spellingShingle Muhammad Ajmal
Jacob Friedman
Qurat Ul Ain Riaz Sipra
Tom Lassar
Rivaroxaban: Expanded Role in Cardiovascular Disease Management—A Literature Review
Cardiovascular Therapeutics
title Rivaroxaban: Expanded Role in Cardiovascular Disease Management—A Literature Review
title_full Rivaroxaban: Expanded Role in Cardiovascular Disease Management—A Literature Review
title_fullStr Rivaroxaban: Expanded Role in Cardiovascular Disease Management—A Literature Review
title_full_unstemmed Rivaroxaban: Expanded Role in Cardiovascular Disease Management—A Literature Review
title_short Rivaroxaban: Expanded Role in Cardiovascular Disease Management—A Literature Review
title_sort rivaroxaban expanded role in cardiovascular disease management a literature review
url http://dx.doi.org/10.1155/2021/8886210
work_keys_str_mv AT muhammadajmal rivaroxabanexpandedroleincardiovasculardiseasemanagementaliteraturereview
AT jacobfriedman rivaroxabanexpandedroleincardiovasculardiseasemanagementaliteraturereview
AT quratulainriazsipra rivaroxabanexpandedroleincardiovasculardiseasemanagementaliteraturereview
AT tomlassar rivaroxabanexpandedroleincardiovasculardiseasemanagementaliteraturereview