Scatter and Blurring Compensation in Inhomogeneous Media Using a Postprocessing Method

An efficient postprocessing method to compensate for the scattering and blurring effects in inhomogeneous medium in SPECT is proposed. A two-dimensional point spread function (2D-PSF) was estimated in the image domain to model the combination of these two physical effects. This 2D-PSF in the inhomog...

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Main Authors: Yan Yan, Gengsheng L. Zeng
Format: Article
Language:English
Published: Wiley 2008-01-01
Series:International Journal of Biomedical Imaging
Online Access:http://dx.doi.org/10.1155/2008/806705
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author Yan Yan
Gengsheng L. Zeng
author_facet Yan Yan
Gengsheng L. Zeng
author_sort Yan Yan
collection DOAJ
description An efficient postprocessing method to compensate for the scattering and blurring effects in inhomogeneous medium in SPECT is proposed. A two-dimensional point spread function (2D-PSF) was estimated in the image domain to model the combination of these two physical effects. This 2D-PSF in the inhomogeneous medium is fitted with an asymmetric Gaussian function based on Monte Carlo simulation results. An efficient further blurring and deconvolution method was used to restore images from the spatially variant 2D-PSF kernel. The compensation is performed using a computer-simulated NCAT phantom and a flanged Jaszczak experimental phantom. The preliminary results demonstrate an improvement in image quality and quantity accuracy with increased image contrast (25% increase compared to uncompensated image) and decreased error (40% decrease compared to uncompensated image). This method also offers an alternative to compensate for scatter and blurring in a more time efficient manner compared to the popular iterative methods. The execution time for this efficient postprocessing method is only a few minutes, which is within the clinically acceptable range.
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institution Kabale University
issn 1687-4188
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language English
publishDate 2008-01-01
publisher Wiley
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series International Journal of Biomedical Imaging
spelling doaj-art-341602239fd4451dbc2335aa9ac742002025-02-03T06:44:31ZengWileyInternational Journal of Biomedical Imaging1687-41881687-41962008-01-01200810.1155/2008/806705806705Scatter and Blurring Compensation in Inhomogeneous Media Using a Postprocessing MethodYan Yan0Gengsheng L. Zeng1Department of Radiology, Utah Center for Advanced Imaging Research, University of Utah, 729 Arapeen Drive, Salt Lake City, UT 84108, USADepartment of Radiology, Utah Center for Advanced Imaging Research, University of Utah, 729 Arapeen Drive, Salt Lake City, UT 84108, USAAn efficient postprocessing method to compensate for the scattering and blurring effects in inhomogeneous medium in SPECT is proposed. A two-dimensional point spread function (2D-PSF) was estimated in the image domain to model the combination of these two physical effects. This 2D-PSF in the inhomogeneous medium is fitted with an asymmetric Gaussian function based on Monte Carlo simulation results. An efficient further blurring and deconvolution method was used to restore images from the spatially variant 2D-PSF kernel. The compensation is performed using a computer-simulated NCAT phantom and a flanged Jaszczak experimental phantom. The preliminary results demonstrate an improvement in image quality and quantity accuracy with increased image contrast (25% increase compared to uncompensated image) and decreased error (40% decrease compared to uncompensated image). This method also offers an alternative to compensate for scatter and blurring in a more time efficient manner compared to the popular iterative methods. The execution time for this efficient postprocessing method is only a few minutes, which is within the clinically acceptable range.http://dx.doi.org/10.1155/2008/806705
spellingShingle Yan Yan
Gengsheng L. Zeng
Scatter and Blurring Compensation in Inhomogeneous Media Using a Postprocessing Method
International Journal of Biomedical Imaging
title Scatter and Blurring Compensation in Inhomogeneous Media Using a Postprocessing Method
title_full Scatter and Blurring Compensation in Inhomogeneous Media Using a Postprocessing Method
title_fullStr Scatter and Blurring Compensation in Inhomogeneous Media Using a Postprocessing Method
title_full_unstemmed Scatter and Blurring Compensation in Inhomogeneous Media Using a Postprocessing Method
title_short Scatter and Blurring Compensation in Inhomogeneous Media Using a Postprocessing Method
title_sort scatter and blurring compensation in inhomogeneous media using a postprocessing method
url http://dx.doi.org/10.1155/2008/806705
work_keys_str_mv AT yanyan scatterandblurringcompensationininhomogeneousmediausingapostprocessingmethod
AT gengshenglzeng scatterandblurringcompensationininhomogeneousmediausingapostprocessingmethod