Movements Execution in Amnestic Mild Cognitive Impairment and Alzheimer’s Disease
We evaluated the relationship between motor and neuropsychological deficits in subjects affected by amnestic Mild Cognitive Impairment (aMCI) and early Alzheimer’s Disease (AD). Kinematics of goal-directed movement of aMCI and AD subjects were compared to those of age-matched control subjects. AD sh...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2007-01-01
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| Series: | Behavioural Neurology |
| Online Access: | http://dx.doi.org/10.1155/2007/845914 |
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| author | Rosolino Camarda Cecilia Camarda Roberto Monastero Silvia Grimaldi Lawrence K. C. Camarda Carmela Pipia Carlo Caltagirone Massimo Gangitano |
| author_facet | Rosolino Camarda Cecilia Camarda Roberto Monastero Silvia Grimaldi Lawrence K. C. Camarda Carmela Pipia Carlo Caltagirone Massimo Gangitano |
| author_sort | Rosolino Camarda |
| collection | DOAJ |
| description | We evaluated the relationship between motor and neuropsychological deficits in subjects affected by amnestic Mild Cognitive Impairment (aMCI) and early Alzheimer’s Disease (AD). Kinematics of goal-directed movement of aMCI and AD subjects were compared to those of age-matched control subjects. AD showed a slowing down of motor performance compared to aMCI and controls. No relationships were found between motor and cognitive performances in both AD and aMCI. Our results suggest that the different motor behaviour between AD and aMCI cannot be related to memory deficits, probably reflecting the initial degeneration of parietal-frontal circuits for movement planning. The onset of motor dysfunction in early AD could represent the transition from aMCI to AD. |
| format | Article |
| id | doaj-art-3401d48ec5184ac899ab1e1324b29af5 |
| institution | Kabale University |
| issn | 0953-4180 1875-8584 |
| language | English |
| publishDate | 2007-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Behavioural Neurology |
| spelling | doaj-art-3401d48ec5184ac899ab1e1324b29af52025-02-03T05:44:11ZengWileyBehavioural Neurology0953-41801875-85842007-01-0118313514210.1155/2007/845914Movements Execution in Amnestic Mild Cognitive Impairment and Alzheimer’s DiseaseRosolino Camarda0Cecilia Camarda1Roberto Monastero2Silvia Grimaldi3Lawrence K. C. Camarda4Carmela Pipia5Carlo Caltagirone6Massimo Gangitano7Laboratory of Epidemiology and Psychology of Aging and Dementia, Section of Neurology, Department of Clinical Neuroscience, University of Palermo, Palermo, ItalyLaboratory of Epidemiology and Psychology of Aging and Dementia, Section of Neurology, Department of Clinical Neuroscience, University of Palermo, Palermo, ItalyLaboratory of Epidemiology and Psychology of Aging and Dementia, Section of Neurology, Department of Clinical Neuroscience, University of Palermo, Palermo, ItalyLaboratory of Epidemiology and Psychology of Aging and Dementia, Section of Neurology, Department of Clinical Neuroscience, University of Palermo, Palermo, ItalyLaboratory of Epidemiology and Psychology of Aging and Dementia, Section of Neurology, Department of Clinical Neuroscience, University of Palermo, Palermo, ItalyLaboratory of Epidemiology and Psychology of Aging and Dementia, Section of Neurology, Department of Clinical Neuroscience, University of Palermo, Palermo, ItalyDepartment of Neurology, University "Tor Vergata", and Fondazione "Santa Lucia" IRCCS, Rome, ItalyLaboratory of Epidemiology and Psychology of Aging and Dementia, Section of Neurology, Department of Clinical Neuroscience, University of Palermo, Palermo, ItalyWe evaluated the relationship between motor and neuropsychological deficits in subjects affected by amnestic Mild Cognitive Impairment (aMCI) and early Alzheimer’s Disease (AD). Kinematics of goal-directed movement of aMCI and AD subjects were compared to those of age-matched control subjects. AD showed a slowing down of motor performance compared to aMCI and controls. No relationships were found between motor and cognitive performances in both AD and aMCI. Our results suggest that the different motor behaviour between AD and aMCI cannot be related to memory deficits, probably reflecting the initial degeneration of parietal-frontal circuits for movement planning. The onset of motor dysfunction in early AD could represent the transition from aMCI to AD.http://dx.doi.org/10.1155/2007/845914 |
| spellingShingle | Rosolino Camarda Cecilia Camarda Roberto Monastero Silvia Grimaldi Lawrence K. C. Camarda Carmela Pipia Carlo Caltagirone Massimo Gangitano Movements Execution in Amnestic Mild Cognitive Impairment and Alzheimer’s Disease Behavioural Neurology |
| title | Movements Execution in Amnestic Mild Cognitive Impairment and Alzheimer’s Disease |
| title_full | Movements Execution in Amnestic Mild Cognitive Impairment and Alzheimer’s Disease |
| title_fullStr | Movements Execution in Amnestic Mild Cognitive Impairment and Alzheimer’s Disease |
| title_full_unstemmed | Movements Execution in Amnestic Mild Cognitive Impairment and Alzheimer’s Disease |
| title_short | Movements Execution in Amnestic Mild Cognitive Impairment and Alzheimer’s Disease |
| title_sort | movements execution in amnestic mild cognitive impairment and alzheimer s disease |
| url | http://dx.doi.org/10.1155/2007/845914 |
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