Acute PM2.5 Exposure in Distinct NSCLC Cell Lines Reveals Strong Oxidative Stress and Therapy Resistance Signatures Through Transcriptomic Analysis

Acute PM2.5 Exposure in Distinct NSCLC Cell Lines Reveals Strong Oxidative Stress and Therapy Resistance Signatures Through Transcriptomic Analysis

Acute PM2.5 exposure has been implicated in lung cancer progression, yet its impact on genetically distinct NSCLC cells remains underexplored. This study investigates how mutation-specific transcriptional responses influence susceptibility to PM2.5-induced oncogenic alterations, focusing on A549 and...

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Bibliographic Details
Main Authors: Aussara Panya, Saruda Thongyim, Pachara Sattayawat, Sahutchai Inwongwan
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Toxics
Subjects:
PM2.5
NSCLC
acute exposure
EGFR mutation
oxidative stress
therapy resistance
Online Access:https://www.mdpi.com/2305-6304/13/6/484
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