First Record of Anguillid Herpesvirus 1 Linked to a Mass Mortality Event in Shortfin Eel (Anguilla bicolor) in Indonesia
Anguillid herpesvirus 1 (AngHV-1), a member of the Alloherpesviridae family, is known to cause high mortality in both wild and farmed eels. Notably, no cases of AngHV-1 infection in Indonesia until June 2023, when a significant mortality rate exceeding 75% among cultured glass eels was documented in...
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Universitas Airlangga, Faculty of Veterinary Medicine
2025-04-01
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| Series: | Jurnal Medik Veteriner |
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| Online Access: | https://e-journal.unair.ac.id/JMV/article/view/62191 |
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| author | Ekky Ilham Romadhona Handang Widantara Aslia Aslia Novi Megawati Arif Rahmat Ardiansyah Annisa Fitri Larassagita Kiki Mariya Dewi Aditia Farman Iding Chaidir Wisnu Sujatmiko Dedy Yaniharto Tatag Budiardi Ratu Siti Aliah Sutanti Sutanti |
| author_facet | Ekky Ilham Romadhona Handang Widantara Aslia Aslia Novi Megawati Arif Rahmat Ardiansyah Annisa Fitri Larassagita Kiki Mariya Dewi Aditia Farman Iding Chaidir Wisnu Sujatmiko Dedy Yaniharto Tatag Budiardi Ratu Siti Aliah Sutanti Sutanti |
| author_sort | Ekky Ilham Romadhona |
| collection | DOAJ |
| description | Anguillid herpesvirus 1 (AngHV-1), a member of the Alloherpesviridae family, is known to cause high mortality in both wild and farmed eels. Notably, no cases of AngHV-1 infection in Indonesia until June 2023, when a significant mortality rate exceeding 75% among cultured glass eels was documented in Bogor, Indonesia. This study investigated the outbreak by collecting 30 diseased fish from multiple cultured tanks to examine clinical symptoms, histopathological changes, and viral presence through PCR targeting the viral DNA polymerase gene. Hemorrhagic lesions in the abdomen and anal regions were the primary clinical symptoms. Histopathological examination revealed hyperplasia, fusion, and epithelial lifting of the gill secondary lamellae. PCR, using 394 bp primer specific for AngHV-1, confirmed 100% infection among the collected samples, indicating rapid viral transmission within the rearing environment. Phylogenetic analysis of partial DNA polymerase amino acid sequences showed that Indonesian AngHV-1 isolate is genetically diverse and shares similarities with strains from China, Taiwan, Canada, and several European countries, suggesting the emergence of a novel strain. This study highlights the urgent need for enhanced biosecurity measures to curb AngHV-1 spread in the Indonesian eel aquaculture sector. |
| format | Article |
| id | doaj-art-33fa5e2aefed4bcd8660efc8fd6b3a27 |
| institution | DOAJ |
| issn | 2615-7497 2581-012X |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Universitas Airlangga, Faculty of Veterinary Medicine |
| record_format | Article |
| series | Jurnal Medik Veteriner |
| spelling | doaj-art-33fa5e2aefed4bcd8660efc8fd6b3a272025-08-20T03:06:52ZengUniversitas Airlangga, Faculty of Veterinary MedicineJurnal Medik Veteriner2615-74972581-012X2025-04-0181134–143134–14310.20473/jmv.vol8.iss1.2025.134–14360358First Record of Anguillid Herpesvirus 1 Linked to a Mass Mortality Event in Shortfin Eel (Anguilla bicolor) in IndonesiaEkky Ilham Romadhona0https://orcid.org/0009-0001-6267-5586Handang Widantara1https://orcid.org/0009-0001-9060-219XAslia Aslia2https://orcid.org/0009-0000-8152-1147Novi Megawati3https://orcid.org/0009-0008-1234-1570Arif Rahmat Ardiansyah4https://orcid.org/0009-0001-9746-0104Annisa Fitri Larassagita5https://orcid.org/0000-0002-3195-9738Kiki Mariya Dewi6https://orcid.org/0009-0004-5447-2318Aditia Farman7Iding Chaidir8https://orcid.org/0009-0000-6312-6469Wisnu Sujatmiko9https://orcid.org/0009-0001-5338-5069Dedy Yaniharto10https://orcid.org/0009-0008-3930-055XTatag Budiardi11https://orcid.org/0000-0002-6703-1608Ratu Siti Aliah12https://orcid.org/0000-0003-0990-5124Sutanti Sutanti13https://orcid.org/0000-0002-0278-9530Research Center for Fishery, National Research and Innovation Agency, Cibinong, West Java 16912, IndonesiaResearch Center for Fishery, National Research and Innovation Agency, Cibinong, West Java 16912, IndonesiaResearch Center for Fishery, National Research and Innovation Agency, Cibinong, West Java 16912, IndonesiaResearch Center for Fishery, National Research and Innovation Agency, Cibinong, West Java 16912, IndonesiaResearch Center for Fishery, National Research and Innovation Agency, Cibinong, West Java 16912, IndonesiaResearch Center for Fishery, National Research and Innovation Agency, Cibinong, West Java 16912, IndonesiaResearch Center for Fishery, National Research and Innovation Agency, Cibinong, West Java 16912, IndonesiaResearch Center for Fishery, National Research and Innovation Agency, Cibinong, West Java 16912, IndonesiaResearch Center for Fishery, National Research and Innovation Agency, Cibinong, West Java 16912, IndonesiaResearch Center for Fishery, National Research and Innovation Agency, Cibinong, West Java 16912, IndonesiaResearch Center for Fishery, National Research and Innovation Agency, Cibinong, West Java 16912, IndonesiaDepartment of Aquaculture, Faculty of Fisheries and Marine Science, IPB University, Bogor, West Java 16680, IndonesiaResearch Center for Fishery, National Research and Innovation Agency, Cibinong, West Java 16912, IndonesiaResearch Center for Fishery, National Research and Innovation Agency, Cibinong, West Java 16912, IndonesiaAnguillid herpesvirus 1 (AngHV-1), a member of the Alloherpesviridae family, is known to cause high mortality in both wild and farmed eels. Notably, no cases of AngHV-1 infection in Indonesia until June 2023, when a significant mortality rate exceeding 75% among cultured glass eels was documented in Bogor, Indonesia. This study investigated the outbreak by collecting 30 diseased fish from multiple cultured tanks to examine clinical symptoms, histopathological changes, and viral presence through PCR targeting the viral DNA polymerase gene. Hemorrhagic lesions in the abdomen and anal regions were the primary clinical symptoms. Histopathological examination revealed hyperplasia, fusion, and epithelial lifting of the gill secondary lamellae. PCR, using 394 bp primer specific for AngHV-1, confirmed 100% infection among the collected samples, indicating rapid viral transmission within the rearing environment. Phylogenetic analysis of partial DNA polymerase amino acid sequences showed that Indonesian AngHV-1 isolate is genetically diverse and shares similarities with strains from China, Taiwan, Canada, and several European countries, suggesting the emergence of a novel strain. This study highlights the urgent need for enhanced biosecurity measures to curb AngHV-1 spread in the Indonesian eel aquaculture sector.https://e-journal.unair.ac.id/JMV/article/view/62191anguillid herpesvirus 1molecular detectionindonesiaphylogenetichistology |
| spellingShingle | Ekky Ilham Romadhona Handang Widantara Aslia Aslia Novi Megawati Arif Rahmat Ardiansyah Annisa Fitri Larassagita Kiki Mariya Dewi Aditia Farman Iding Chaidir Wisnu Sujatmiko Dedy Yaniharto Tatag Budiardi Ratu Siti Aliah Sutanti Sutanti First Record of Anguillid Herpesvirus 1 Linked to a Mass Mortality Event in Shortfin Eel (Anguilla bicolor) in Indonesia Jurnal Medik Veteriner anguillid herpesvirus 1 molecular detection indonesia phylogenetic histology |
| title | First Record of Anguillid Herpesvirus 1 Linked to a Mass Mortality Event in Shortfin Eel (Anguilla bicolor) in Indonesia |
| title_full | First Record of Anguillid Herpesvirus 1 Linked to a Mass Mortality Event in Shortfin Eel (Anguilla bicolor) in Indonesia |
| title_fullStr | First Record of Anguillid Herpesvirus 1 Linked to a Mass Mortality Event in Shortfin Eel (Anguilla bicolor) in Indonesia |
| title_full_unstemmed | First Record of Anguillid Herpesvirus 1 Linked to a Mass Mortality Event in Shortfin Eel (Anguilla bicolor) in Indonesia |
| title_short | First Record of Anguillid Herpesvirus 1 Linked to a Mass Mortality Event in Shortfin Eel (Anguilla bicolor) in Indonesia |
| title_sort | first record of anguillid herpesvirus 1 linked to a mass mortality event in shortfin eel anguilla bicolor in indonesia |
| topic | anguillid herpesvirus 1 molecular detection indonesia phylogenetic histology |
| url | https://e-journal.unair.ac.id/JMV/article/view/62191 |
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