Glucagon-like peptide-1 receptor agonists inhibit the progression of malignant pleural effusion in obese mice by regulating the metabolism of pleural effusion

Glucagon-like peptide-1 receptor agonists inhibit the progression of malignant pleural effusion in obese mice by regulating the metabolism of pleural effusion

Abstract Background Diabetes is a prevalent endocrine disease frequently linked to obesity and associated with an increased cancer risk and mortality. Malignant pleural effusion (MPE), a common metastatic manifestation of advanced cancer, poses significant challenges in clinical management. This stu...

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Bibliographic Details
Main Authors: Ming-Ming Shao, Shu-Feng Dong, Qing-Yu Chen, Rui-Qi Wei, Feng-Shuang Yi
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Journal of Translational Medicine
Subjects:
MPE
Obesity
GLP-1RA
Metabolomics
Purine metabolism
Online Access:https://doi.org/10.1186/s12967-025-06875-8
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