Ultrasound Microbubbles Enhance the Neuroprotective Effect of Mouse Nerve Growth Factor on Intraocular Hypertension-Induced Neuroretina Damage in Rabbits
Ultrasound microbubble combined optic protection drugs have obvious protective effect on optic nerve damage. This way of targeting drug delivery is becoming more simple, not through the whole body metabolism, avoiding drug via blood circulation when facing the decomposition and the environment in th...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2016-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2016/4235923 |
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| author | Xiaoli Shen Lina Huang Dahui Ma Jun Zhao Yi Xie Qiang Li Aineng Zeng Kun Zeng Ruyin Tian Tianfu Wang Siping Chen |
| author_facet | Xiaoli Shen Lina Huang Dahui Ma Jun Zhao Yi Xie Qiang Li Aineng Zeng Kun Zeng Ruyin Tian Tianfu Wang Siping Chen |
| author_sort | Xiaoli Shen |
| collection | DOAJ |
| description | Ultrasound microbubble combined optic protection drugs have obvious protective effect on optic nerve damage. This way of targeting drug delivery is becoming more simple, not through the whole body metabolism, avoiding drug via blood circulation when facing the decomposition and the environment in the interference and destruction process of drugs, to maximize the guarantee to reach target organs of drug concentration and to reache the maximum therapeutic effect. The technique of ultrasound microbubbles is safe, controllable, nonimmunogenic, and repeatable. It provides us with a novel idea in the administration of neuroprotective drugs. |
| format | Article |
| id | doaj-art-33db64e5ac204003a0bdff5ee276d6f6 |
| institution | Kabale University |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-33db64e5ac204003a0bdff5ee276d6f62025-02-03T01:07:50ZengWileyJournal of Ophthalmology2090-004X2090-00582016-01-01201610.1155/2016/42359234235923Ultrasound Microbubbles Enhance the Neuroprotective Effect of Mouse Nerve Growth Factor on Intraocular Hypertension-Induced Neuroretina Damage in RabbitsXiaoli Shen0Lina Huang1Dahui Ma2Jun Zhao3Yi Xie4Qiang Li5Aineng Zeng6Kun Zeng7Ruyin Tian8Tianfu Wang9Siping Chen10Affiliated Shenzhen Eye Hospital of Jinan University, Shenzhen, Guangdong, ChinaAffiliated Shenzhen Eye Hospital of Jinan University, Shenzhen, Guangdong, ChinaAffiliated Shenzhen Eye Hospital of Jinan University, Shenzhen, Guangdong, ChinaAffiliated Shenzhen Eye Hospital of Jinan University, Shenzhen, Guangdong, ChinaAffiliated Shenzhen Eye Hospital of Jinan University, Shenzhen, Guangdong, ChinaShenzhen People’s Hospital, Shenzhen, Guangdong, ChinaAffiliated Shenzhen Eye Hospital of Jinan University, Shenzhen, Guangdong, ChinaAffiliated Shenzhen Eye Hospital of Jinan University, Shenzhen, Guangdong, ChinaAffiliated Shenzhen Eye Hospital of Jinan University, Shenzhen, Guangdong, ChinaShenzhen University, Shenzhen, Guangdong, ChinaShenzhen University, Shenzhen, Guangdong, ChinaUltrasound microbubble combined optic protection drugs have obvious protective effect on optic nerve damage. This way of targeting drug delivery is becoming more simple, not through the whole body metabolism, avoiding drug via blood circulation when facing the decomposition and the environment in the interference and destruction process of drugs, to maximize the guarantee to reach target organs of drug concentration and to reache the maximum therapeutic effect. The technique of ultrasound microbubbles is safe, controllable, nonimmunogenic, and repeatable. It provides us with a novel idea in the administration of neuroprotective drugs.http://dx.doi.org/10.1155/2016/4235923 |
| spellingShingle | Xiaoli Shen Lina Huang Dahui Ma Jun Zhao Yi Xie Qiang Li Aineng Zeng Kun Zeng Ruyin Tian Tianfu Wang Siping Chen Ultrasound Microbubbles Enhance the Neuroprotective Effect of Mouse Nerve Growth Factor on Intraocular Hypertension-Induced Neuroretina Damage in Rabbits Journal of Ophthalmology |
| title | Ultrasound Microbubbles Enhance the Neuroprotective Effect of Mouse Nerve Growth Factor on Intraocular Hypertension-Induced Neuroretina Damage in Rabbits |
| title_full | Ultrasound Microbubbles Enhance the Neuroprotective Effect of Mouse Nerve Growth Factor on Intraocular Hypertension-Induced Neuroretina Damage in Rabbits |
| title_fullStr | Ultrasound Microbubbles Enhance the Neuroprotective Effect of Mouse Nerve Growth Factor on Intraocular Hypertension-Induced Neuroretina Damage in Rabbits |
| title_full_unstemmed | Ultrasound Microbubbles Enhance the Neuroprotective Effect of Mouse Nerve Growth Factor on Intraocular Hypertension-Induced Neuroretina Damage in Rabbits |
| title_short | Ultrasound Microbubbles Enhance the Neuroprotective Effect of Mouse Nerve Growth Factor on Intraocular Hypertension-Induced Neuroretina Damage in Rabbits |
| title_sort | ultrasound microbubbles enhance the neuroprotective effect of mouse nerve growth factor on intraocular hypertension induced neuroretina damage in rabbits |
| url | http://dx.doi.org/10.1155/2016/4235923 |
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