Thyroid hormones inhibit tumor progression and enhance the antitumor activity of lenvatinib in hepatocellular carcinoma via reprogramming glucose metabolism

Thyroid hormones inhibit tumor progression and enhance the antitumor activity of lenvatinib in hepatocellular carcinoma via reprogramming glucose metabolism

Abstract Thyroid hormones (THs) dysfunctions have been demonstrated to be associated with the risk of developing different types of cancers. The role of THs in regulating hepatocellular carcinoma (HCC) progression is still controversial. We demonstrated that T3 can inhibit HCC progression by enhanci...

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Main Authors: Chun‑Cheng Yang, Yu-Chuan Yan, Guo‑Qiang Pan, Guang-Xiao Meng, Xiao Zhang, Lun-Jie Yan, Zi-Niu Ding, Dong-Xu Wang, Rui-Zhe Li, Guang-Zhen Li, Zhao‑Ru Dong, Tao Li
Format: Article
Language:English
Published: Nature Publishing Group 2025-03-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-025-02378-z
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