Response to Statin Therapy in Obstructive Sleep Apnea Syndrome: A Multicenter Randomized Controlled Trial
Rationale. Accumulated evidence implicates sympathetic activation as inducing oxidative stress and systemic inflammation, which in turn lead to hypertension, endothelial dysfunction, and atherosclerosis in obstructive sleep apnea (OSA). Statins through their pleiotropic properties may modify inflamm...
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Main Authors: | Marie Joyeux-Faure, Renaud Tamisier, Jean-Philippe Baguet, Sonia Dias-Domingos, Stephen Perrig, Georges Leftheriotis, Jean-Paul Janssens, Wojciech Trzepizur, Sandrine H. Launois, Françoise Stanke-Labesque, Patrick A. Lévy, Frédéric Gagnadoux, Jean-Louis Pepin |
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Format: | Article |
Language: | English |
Published: |
Wiley
2014-01-01
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Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1155/2014/423120 |
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