Benzo[1,2-b:6,5-b’]dithiophene-4,5-diamine: A New Fluorescent Probe for the High-Sensitivity and Real-Time Visual Monitoring of Phosgene
The detection of highly toxic chemicals such as phosgene is crucial for addressing the severe threats to human health and public safety posed by terrorist attacks and industrial mishaps. However, timely and precise monitoring of phosgene at a low cost remains a significant challenge. This work is th...
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2025-01-01
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| author | Yingzhen Zhang Jun Xiao Ruiying Peng Xueliang Feng Haimei Mao Kunming Liu Zhenzhong Liu Chunxin Ma |
| author_facet | Yingzhen Zhang Jun Xiao Ruiying Peng Xueliang Feng Haimei Mao Kunming Liu Zhenzhong Liu Chunxin Ma |
| author_sort | Yingzhen Zhang |
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| description | The detection of highly toxic chemicals such as phosgene is crucial for addressing the severe threats to human health and public safety posed by terrorist attacks and industrial mishaps. However, timely and precise monitoring of phosgene at a low cost remains a significant challenge. This work is the first to report a novel fluorescent system based on the Intramolecular Charge Transfer (ICT) effect, which can rapidly detect phosgene in both solution and gas phases with high sensitivity by integrating a benzo[1,2-b:6,5-b’]dithiophene-4,5-diamine (BDTA) probe. Among existing detecting methods, this fluorescent system stands out as it can respond to phosgene within a mere 30 s and has a detection limit as low as 0.16 μM in solution. Furthermore, the sensing mechanism was rigorously validated through high-resolution mass spectrometry (HRMS) and density functional theory (DFT) calculations. As a result, this fluorescent probing system for phosgene can be effectively adapted for real-time, high-sensitivity sensing and used as a test strip for visual monitoring without the need for specific equipment, which will also provide a new strategy for the fluorescent detection of other toxic materials. |
| format | Article |
| id | doaj-art-33bab890de854656a58f536aa3511f9e |
| institution | Kabale University |
| issn | 1424-8220 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Sensors |
| spelling | doaj-art-33bab890de854656a58f536aa3511f9e2025-01-24T13:48:48ZengMDPI AGSensors1424-82202025-01-0125240710.3390/s25020407Benzo[1,2-b:6,5-b’]dithiophene-4,5-diamine: A New Fluorescent Probe for the High-Sensitivity and Real-Time Visual Monitoring of PhosgeneYingzhen Zhang0Jun Xiao1Ruiying Peng2Xueliang Feng3Haimei Mao4Kunming Liu5Zhenzhong Liu6Chunxin Ma7School of Chemistry and Chemical Engineering, Jiangxi University of Science and Technology, Ganzhou 341000, ChinaSchool of Chemistry and Chemical Engineering, Jiangxi University of Science and Technology, Ganzhou 341000, ChinaSchool of Chemistry and Chemical Engineering, Jiangxi University of Science and Technology, Ganzhou 341000, ChinaState Key Laboratory of Marine Resource Utilization in South China Sea, School of Chemistry and Chemical Engineering, Hainan University, Haikou 570228, ChinaKey Laboratory of Quality Safe Evaluation and Research of Degradable Material, State Administration for Market Regulation, Hainan Academy of Inspection and Testing, Haikou 570203, ChinaSchool of Chemistry and Chemical Engineering, Jiangxi University of Science and Technology, Ganzhou 341000, ChinaTaizhou Key Laboratory of Medical Devices and Advanced Materials, Taizhou Institute of Zhejiang University, Taizhou 318000, ChinaState Key Laboratory of Marine Resource Utilization in South China Sea, School of Chemistry and Chemical Engineering, Hainan University, Haikou 570228, ChinaThe detection of highly toxic chemicals such as phosgene is crucial for addressing the severe threats to human health and public safety posed by terrorist attacks and industrial mishaps. However, timely and precise monitoring of phosgene at a low cost remains a significant challenge. This work is the first to report a novel fluorescent system based on the Intramolecular Charge Transfer (ICT) effect, which can rapidly detect phosgene in both solution and gas phases with high sensitivity by integrating a benzo[1,2-b:6,5-b’]dithiophene-4,5-diamine (BDTA) probe. Among existing detecting methods, this fluorescent system stands out as it can respond to phosgene within a mere 30 s and has a detection limit as low as 0.16 μM in solution. Furthermore, the sensing mechanism was rigorously validated through high-resolution mass spectrometry (HRMS) and density functional theory (DFT) calculations. As a result, this fluorescent probing system for phosgene can be effectively adapted for real-time, high-sensitivity sensing and used as a test strip for visual monitoring without the need for specific equipment, which will also provide a new strategy for the fluorescent detection of other toxic materials.https://www.mdpi.com/1424-8220/25/2/407fluorescent chemosensorsphosgenebenzo[1,2-b:4,3-b’]dithiophenereal-time monitoringvisual test strip |
| spellingShingle | Yingzhen Zhang Jun Xiao Ruiying Peng Xueliang Feng Haimei Mao Kunming Liu Zhenzhong Liu Chunxin Ma Benzo[1,2-b:6,5-b’]dithiophene-4,5-diamine: A New Fluorescent Probe for the High-Sensitivity and Real-Time Visual Monitoring of Phosgene Sensors fluorescent chemosensors phosgene benzo[1,2-b:4,3-b’]dithiophene real-time monitoring visual test strip |
| title | Benzo[1,2-b:6,5-b’]dithiophene-4,5-diamine: A New Fluorescent Probe for the High-Sensitivity and Real-Time Visual Monitoring of Phosgene |
| title_full | Benzo[1,2-b:6,5-b’]dithiophene-4,5-diamine: A New Fluorescent Probe for the High-Sensitivity and Real-Time Visual Monitoring of Phosgene |
| title_fullStr | Benzo[1,2-b:6,5-b’]dithiophene-4,5-diamine: A New Fluorescent Probe for the High-Sensitivity and Real-Time Visual Monitoring of Phosgene |
| title_full_unstemmed | Benzo[1,2-b:6,5-b’]dithiophene-4,5-diamine: A New Fluorescent Probe for the High-Sensitivity and Real-Time Visual Monitoring of Phosgene |
| title_short | Benzo[1,2-b:6,5-b’]dithiophene-4,5-diamine: A New Fluorescent Probe for the High-Sensitivity and Real-Time Visual Monitoring of Phosgene |
| title_sort | benzo 1 2 b 6 5 b dithiophene 4 5 diamine a new fluorescent probe for the high sensitivity and real time visual monitoring of phosgene |
| topic | fluorescent chemosensors phosgene benzo[1,2-b:4,3-b’]dithiophene real-time monitoring visual test strip |
| url | https://www.mdpi.com/1424-8220/25/2/407 |
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