Intraovarian injection of 3D-MSC-EVs-ECM gel significantly improved rat ovarian function after chemotherapy
Abstract Background Restoring the function of the ovary is important for chemotherapy-induced ovarian failure (COF) patients. Stem cell and extracellular vesicles (EVs) therapy show promise but need further improvement. Methods Human umbilical cord mesenchymal stem cells (hUC-MSCs) were primarily cu...
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| Main Authors: | Yaping Zhang, Dong Li, Yi Han, Min Wu, Shule Zhang, Huixian Ma, Linghong Liu, Xiuli Ju |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2024-10-01
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| Series: | Reproductive Biology and Endocrinology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12958-024-01299-3 |
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