Intraovarian injection of 3D-MSC-EVs-ECM gel significantly improved rat ovarian function after chemotherapy

Intraovarian injection of 3D-MSC-EVs-ECM gel significantly improved rat ovarian function after chemotherapy

Abstract Background Restoring the function of the ovary is important for chemotherapy-induced ovarian failure (COF) patients. Stem cell and extracellular vesicles (EVs) therapy show promise but need further improvement. Methods Human umbilical cord mesenchymal stem cells (hUC-MSCs) were primarily cu...

Full description

Saved in:
Bibliographic Details
Main Authors: Yaping Zhang, Dong Li, Yi Han, Min Wu, Shule Zhang, Huixian Ma, Linghong Liu, Xiuli Ju
Format: Article
Language:English
Published: BMC 2024-10-01
Series:Reproductive Biology and Endocrinology
Subjects:
Cyclophosphamide
Extracellular vesicles
Gel
Mesenchymal stem cell
Ovarian failure
Three-dimensional culture
Online Access:https://doi.org/10.1186/s12958-024-01299-3
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1186/s12958-024-01299-3

Similar Items