Cognitive Impairments in Viral Hepatitis Patients: Causes, Manifestations, and Impact on Quality of Life

Viral hepatitis, primarily caused by hepatitis B virus and hepatitis C virus, is widely recognized for its impact on liver function, but emerging evidence suggests it also affects cognitive function. This review explores the causes, manifestations, and impact of cognitive impairments in patients wit...

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Main Author: Tatyana Vasiliyevna Polukchi
Format: Article
Language:English
Published: Rambam Health Care Campus 2025-01-01
Series:Rambam Maimonides Medical Journal
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Online Access:https://www.rmmj.org.il/issues/65/1998/manuscript
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author Tatyana Vasiliyevna Polukchi
author_facet Tatyana Vasiliyevna Polukchi
author_sort Tatyana Vasiliyevna Polukchi
collection DOAJ
description Viral hepatitis, primarily caused by hepatitis B virus and hepatitis C virus, is widely recognized for its impact on liver function, but emerging evidence suggests it also affects cognitive function. This review explores the causes, manifestations, and impact of cognitive impairments in patients with viral hepatitis, to better understand this often-overlooked aspect of the disease. A literature review was conducted, focusing on studies published in PubMed up to August 2024. Key areas covered include the pathophysiological mechanisms behind cognitive impairment in viral hepatitis, clinical manifestations observed in affected patients, the implications for their daily functioning and overall well-being, and the tools used in cognitive assessments. Common manifestations included deficits in attention, memory, executive function, and psychomotor speed. These cognitive challenges can significantly impact daily activities, occupational performance, and social interactions, contributing to reduced quality of life. Cognitive impairments in viral hepatitis patients represent a significant concern that extends beyond liver health. Recognizing and addressing these cognitive issues are crucial for improving patient outcomes. Enhanced diagnostic strategies and targeted interventions are needed to better manage cognitive symptoms and support affected individuals in maintaining their quality of life. This narrative review aims to enhance clinical practice and inform future research directions.
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spelling doaj-art-339be37331e64cb5b2377382ab44de782025-01-30T08:30:00ZengRambam Health Care CampusRambam Maimonides Medical Journal2076-91722025-01-01161e000310.5041/RMMJ.10539Cognitive Impairments in Viral Hepatitis Patients: Causes, Manifestations, and Impact on Quality of LifeTatyana Vasiliyevna Polukchi0Department of Neurosurgery, South Kazakhstan Medical Academy, Shymkent, Republic of KazakhstanViral hepatitis, primarily caused by hepatitis B virus and hepatitis C virus, is widely recognized for its impact on liver function, but emerging evidence suggests it also affects cognitive function. This review explores the causes, manifestations, and impact of cognitive impairments in patients with viral hepatitis, to better understand this often-overlooked aspect of the disease. A literature review was conducted, focusing on studies published in PubMed up to August 2024. Key areas covered include the pathophysiological mechanisms behind cognitive impairment in viral hepatitis, clinical manifestations observed in affected patients, the implications for their daily functioning and overall well-being, and the tools used in cognitive assessments. Common manifestations included deficits in attention, memory, executive function, and psychomotor speed. These cognitive challenges can significantly impact daily activities, occupational performance, and social interactions, contributing to reduced quality of life. Cognitive impairments in viral hepatitis patients represent a significant concern that extends beyond liver health. Recognizing and addressing these cognitive issues are crucial for improving patient outcomes. Enhanced diagnostic strategies and targeted interventions are needed to better manage cognitive symptoms and support affected individuals in maintaining their quality of life. This narrative review aims to enhance clinical practice and inform future research directions.https://www.rmmj.org.il/issues/65/1998/manuscriptcognitive impairmenthepatic encephalopathyneurocognitive functionquality of lifeviral hepatitis
spellingShingle Tatyana Vasiliyevna Polukchi
Cognitive Impairments in Viral Hepatitis Patients: Causes, Manifestations, and Impact on Quality of Life
Rambam Maimonides Medical Journal
cognitive impairment
hepatic encephalopathy
neurocognitive function
quality of life
viral hepatitis
title Cognitive Impairments in Viral Hepatitis Patients: Causes, Manifestations, and Impact on Quality of Life
title_full Cognitive Impairments in Viral Hepatitis Patients: Causes, Manifestations, and Impact on Quality of Life
title_fullStr Cognitive Impairments in Viral Hepatitis Patients: Causes, Manifestations, and Impact on Quality of Life
title_full_unstemmed Cognitive Impairments in Viral Hepatitis Patients: Causes, Manifestations, and Impact on Quality of Life
title_short Cognitive Impairments in Viral Hepatitis Patients: Causes, Manifestations, and Impact on Quality of Life
title_sort cognitive impairments in viral hepatitis patients causes manifestations and impact on quality of life
topic cognitive impairment
hepatic encephalopathy
neurocognitive function
quality of life
viral hepatitis
url https://www.rmmj.org.il/issues/65/1998/manuscript
work_keys_str_mv AT tatyanavasiliyevnapolukchi cognitiveimpairmentsinviralhepatitispatientscausesmanifestationsandimpactonqualityoflife