Cost-utility and cost–benefit analysis of a multi-component intervention (NEXpro) for neck-related symptoms in Swiss office workers
Abstract Background Neck pain is a significant public health issue, especially among office workers, with a prevalence ranging from 42 to 68%. This study aimed to evaluate the cost-utility and cost-benefit of a multi-component intervention targeting neck pain in the general population of office work...
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2025-01-01
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| Online Access: | https://doi.org/10.1186/s12889-024-21103-6 |
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| author | Beatrice Brunner Andrea Martina Aegerter Venerina Johnston Thomas Volken Manja Deforth Gisela Sjøgaard Achim Elfering Markus Melloh the NEXpro Collaboration Group |
| author_facet | Beatrice Brunner Andrea Martina Aegerter Venerina Johnston Thomas Volken Manja Deforth Gisela Sjøgaard Achim Elfering Markus Melloh the NEXpro Collaboration Group |
| author_sort | Beatrice Brunner |
| collection | DOAJ |
| description | Abstract Background Neck pain is a significant public health issue, especially among office workers, with a prevalence ranging from 42 to 68%. This study aimed to evaluate the cost-utility and cost-benefit of a multi-component intervention targeting neck pain in the general population of office workers in Switzerland. The 12-week multi-component intervention consisted of neck exercises, health promotion information workshops, and workplace ergonomics sessions. Methods The study was designed as a stepped-wedge cluster randomized controlled trial and assessed using an employer’s perspective. The main analysis focused on the immediate post-intervention period. Long-term effects were examined in a subsample at the 4, 8, and 12-month follow-ups. The intervention effects on costs and quality-adjusted life years (QALYs) were estimated using generalized linear mixed-effects models, controlling for confounding factors. Incremental cost-effectiveness ratios (ICERs) and cost-effectiveness acceptability curves were presented, along with calculations of the break-even point and the return on investment. Various sensitivity analyses were performed. Results A total of 120 office workers participated in the trial, with 100 completing the intervention period and 94 completing the entire study. The main analysis included 392 observations. The intervention had a significant positive effect on QALYs and a nonsignificant effect on costs. The ICER was estimated at -25,325 per QALY gain, and the probability of the intervention being cost saving was estimated at 88%. The break-even point was reached one week after the end of the intervention. Conclusion The multi-component intervention is likely to reduce company costs and simultaneously improve the quality of life of employees. However, the implementation of such interventions critically depends on evidence of their cost-effectiveness. As there is still a large research gap in this area, future studies are needed. Trial registration ClinicalTrials.gov, NCT04169646 . Registered 15 November 2019-Retrospectively registered. Trial protocol Aegerter AM, Deforth M, Johnston V, Ernst MJ, Volken T, Luomajoki H, et al. On-site multi-component intervention to improve productivity and reduce the economic and personal burden of neck pain in Swiss office-workers (NEXpro): protocol for a cluster-randomized controlled trial. BMC Musculoskelet Disord. 2020;21(1):391. https://doi.org/10.1186/s12891-020-03388-x . |
| format | Article |
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| institution | Kabale University |
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| spelling | doaj-art-33847f7f8aff4b2ebe96e8055db631652025-01-19T12:41:57ZengBMCBMC Public Health1471-24582025-01-0125111310.1186/s12889-024-21103-6Cost-utility and cost–benefit analysis of a multi-component intervention (NEXpro) for neck-related symptoms in Swiss office workersBeatrice Brunner0Andrea Martina Aegerter1Venerina Johnston2Thomas Volken3Manja Deforth4Gisela Sjøgaard5Achim Elfering6Markus Melloh7the NEXpro Collaboration GroupZHAW Zurich University of Applied Sciences, Winterthur Institute of Health EconomicsZHAW Zurich University of Applied Sciences, School of Health Sciences, Institute of Public HealthUniversity of Southern Queensland, School of Health and Medical SciencesZHAW Zurich University of Applied Sciences, School of Health Sciences, Institute of Public HealthZHAW Zurich University of Applied Sciences, School of Health Sciences, Institute of Public HealthUniversity of Southern Denmark, Department of Sports Science and Clinical BiomechanicsUniversity of Bern, Institute of PsychologyZHAW Zurich University of Applied Sciences, School of Health Sciences, Institute of Public HealthAbstract Background Neck pain is a significant public health issue, especially among office workers, with a prevalence ranging from 42 to 68%. This study aimed to evaluate the cost-utility and cost-benefit of a multi-component intervention targeting neck pain in the general population of office workers in Switzerland. The 12-week multi-component intervention consisted of neck exercises, health promotion information workshops, and workplace ergonomics sessions. Methods The study was designed as a stepped-wedge cluster randomized controlled trial and assessed using an employer’s perspective. The main analysis focused on the immediate post-intervention period. Long-term effects were examined in a subsample at the 4, 8, and 12-month follow-ups. The intervention effects on costs and quality-adjusted life years (QALYs) were estimated using generalized linear mixed-effects models, controlling for confounding factors. Incremental cost-effectiveness ratios (ICERs) and cost-effectiveness acceptability curves were presented, along with calculations of the break-even point and the return on investment. Various sensitivity analyses were performed. Results A total of 120 office workers participated in the trial, with 100 completing the intervention period and 94 completing the entire study. The main analysis included 392 observations. The intervention had a significant positive effect on QALYs and a nonsignificant effect on costs. The ICER was estimated at -25,325 per QALY gain, and the probability of the intervention being cost saving was estimated at 88%. The break-even point was reached one week after the end of the intervention. Conclusion The multi-component intervention is likely to reduce company costs and simultaneously improve the quality of life of employees. However, the implementation of such interventions critically depends on evidence of their cost-effectiveness. As there is still a large research gap in this area, future studies are needed. Trial registration ClinicalTrials.gov, NCT04169646 . Registered 15 November 2019-Retrospectively registered. Trial protocol Aegerter AM, Deforth M, Johnston V, Ernst MJ, Volken T, Luomajoki H, et al. On-site multi-component intervention to improve productivity and reduce the economic and personal burden of neck pain in Swiss office-workers (NEXpro): protocol for a cluster-randomized controlled trial. BMC Musculoskelet Disord. 2020;21(1):391. https://doi.org/10.1186/s12891-020-03388-x .https://doi.org/10.1186/s12889-024-21103-6Cost-utilityNeck painWorkplace interventionHealth economic evaluationQuality adjusted life yearsPresenteeism |
| spellingShingle | Beatrice Brunner Andrea Martina Aegerter Venerina Johnston Thomas Volken Manja Deforth Gisela Sjøgaard Achim Elfering Markus Melloh the NEXpro Collaboration Group Cost-utility and cost–benefit analysis of a multi-component intervention (NEXpro) for neck-related symptoms in Swiss office workers BMC Public Health Cost-utility Neck pain Workplace intervention Health economic evaluation Quality adjusted life years Presenteeism |
| title | Cost-utility and cost–benefit analysis of a multi-component intervention (NEXpro) for neck-related symptoms in Swiss office workers |
| title_full | Cost-utility and cost–benefit analysis of a multi-component intervention (NEXpro) for neck-related symptoms in Swiss office workers |
| title_fullStr | Cost-utility and cost–benefit analysis of a multi-component intervention (NEXpro) for neck-related symptoms in Swiss office workers |
| title_full_unstemmed | Cost-utility and cost–benefit analysis of a multi-component intervention (NEXpro) for neck-related symptoms in Swiss office workers |
| title_short | Cost-utility and cost–benefit analysis of a multi-component intervention (NEXpro) for neck-related symptoms in Swiss office workers |
| title_sort | cost utility and cost benefit analysis of a multi component intervention nexpro for neck related symptoms in swiss office workers |
| topic | Cost-utility Neck pain Workplace intervention Health economic evaluation Quality adjusted life years Presenteeism |
| url | https://doi.org/10.1186/s12889-024-21103-6 |
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