Obesity-Related Asthma: Immune Regulation and Potential Targeted Therapies
Obesity, one of the most severe public health problems of the 21st century, is a common metabolic syndrome due to excess body fat. The incidence and severity of obesity-related asthma have undergone a dramatic increase. Because obesity-related asthma is poorly controlled using conventional therapies...
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| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2018-01-01
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| Series: | Journal of Immunology Research |
| Online Access: | http://dx.doi.org/10.1155/2018/1943497 |
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| _version_ | 1832561695091851264 |
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| author | Yuze Yuan Nan Ran Lingxin Xiong Guoqiang Wang Xuewa Guan Ziyan Wang Yingqiao Guo Zhiqiang Pang Keyong Fang Junying Lu Chao Zhang Ruipeng Zheng Jingtong Zheng Jie Ma Fang Wang |
| author_facet | Yuze Yuan Nan Ran Lingxin Xiong Guoqiang Wang Xuewa Guan Ziyan Wang Yingqiao Guo Zhiqiang Pang Keyong Fang Junying Lu Chao Zhang Ruipeng Zheng Jingtong Zheng Jie Ma Fang Wang |
| author_sort | Yuze Yuan |
| collection | DOAJ |
| description | Obesity, one of the most severe public health problems of the 21st century, is a common metabolic syndrome due to excess body fat. The incidence and severity of obesity-related asthma have undergone a dramatic increase. Because obesity-related asthma is poorly controlled using conventional therapies, alternative and complementary therapies are urgently needed. Lipid metabolism may be abnormal in obesity-related asthma, and immune modulation therapies need to be investigated. Herein, we describe the immune regulators of lipid metabolism in obesity as well as the interplay of obesity and asthma. These lay the foundations for targeted therapies in terms of direct and indirect immune regulators of lipid metabolism, which ultimately help provide effective control of obesity-related asthma with a feasible treatment strategy. |
| format | Article |
| id | doaj-art-33775e4932874a0ca99f7feecbdd5a73 |
| institution | Kabale University |
| issn | 2314-8861 2314-7156 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Immunology Research |
| spelling | doaj-art-33775e4932874a0ca99f7feecbdd5a732025-02-03T01:24:26ZengWileyJournal of Immunology Research2314-88612314-71562018-01-01201810.1155/2018/19434971943497Obesity-Related Asthma: Immune Regulation and Potential Targeted TherapiesYuze Yuan0Nan Ran1Lingxin Xiong2Guoqiang Wang3Xuewa Guan4Ziyan Wang5Yingqiao Guo6Zhiqiang Pang7Keyong Fang8Junying Lu9Chao Zhang10Ruipeng Zheng11Jingtong Zheng12Jie Ma13Fang Wang14Department of Pathogeny Biology, College of Basic Medical Sciences, Jilin University, Changchun 130021, ChinaDepartment of Pathogeny Biology, College of Basic Medical Sciences, Jilin University, Changchun 130021, ChinaDepartment of Pathogeny Biology, College of Basic Medical Sciences, Jilin University, Changchun 130021, ChinaDepartment of Pathogeny Biology, College of Basic Medical Sciences, Jilin University, Changchun 130021, ChinaDepartment of Pathogeny Biology, College of Basic Medical Sciences, Jilin University, Changchun 130021, ChinaDepartment of Pathogeny Biology, College of Basic Medical Sciences, Jilin University, Changchun 130021, ChinaDepartment of Pathogeny Biology, College of Basic Medical Sciences, Jilin University, Changchun 130021, ChinaDepartment of Pathogeny Biology, College of Basic Medical Sciences, Jilin University, Changchun 130021, ChinaDepartment of Pathogeny Biology, College of Basic Medical Sciences, Jilin University, Changchun 130021, ChinaDepartment of Pathogeny Biology, College of Basic Medical Sciences, Jilin University, Changchun 130021, ChinaDepartment of Pathogeny Biology, College of Basic Medical Sciences, Jilin University, Changchun 130021, ChinaDepartment of Pathogeny Biology, College of Basic Medical Sciences, Jilin University, Changchun 130021, ChinaDepartment of Pathogeny Biology, College of Basic Medical Sciences, Jilin University, Changchun 130021, ChinaSchool of Pharmaceutical Sciences, Jilin University, Changchun 130021, ChinaDepartment of Pathogeny Biology, College of Basic Medical Sciences, Jilin University, Changchun 130021, ChinaObesity, one of the most severe public health problems of the 21st century, is a common metabolic syndrome due to excess body fat. The incidence and severity of obesity-related asthma have undergone a dramatic increase. Because obesity-related asthma is poorly controlled using conventional therapies, alternative and complementary therapies are urgently needed. Lipid metabolism may be abnormal in obesity-related asthma, and immune modulation therapies need to be investigated. Herein, we describe the immune regulators of lipid metabolism in obesity as well as the interplay of obesity and asthma. These lay the foundations for targeted therapies in terms of direct and indirect immune regulators of lipid metabolism, which ultimately help provide effective control of obesity-related asthma with a feasible treatment strategy.http://dx.doi.org/10.1155/2018/1943497 |
| spellingShingle | Yuze Yuan Nan Ran Lingxin Xiong Guoqiang Wang Xuewa Guan Ziyan Wang Yingqiao Guo Zhiqiang Pang Keyong Fang Junying Lu Chao Zhang Ruipeng Zheng Jingtong Zheng Jie Ma Fang Wang Obesity-Related Asthma: Immune Regulation and Potential Targeted Therapies Journal of Immunology Research |
| title | Obesity-Related Asthma: Immune Regulation and Potential Targeted Therapies |
| title_full | Obesity-Related Asthma: Immune Regulation and Potential Targeted Therapies |
| title_fullStr | Obesity-Related Asthma: Immune Regulation and Potential Targeted Therapies |
| title_full_unstemmed | Obesity-Related Asthma: Immune Regulation and Potential Targeted Therapies |
| title_short | Obesity-Related Asthma: Immune Regulation and Potential Targeted Therapies |
| title_sort | obesity related asthma immune regulation and potential targeted therapies |
| url | http://dx.doi.org/10.1155/2018/1943497 |
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