Supraglottic Neuroendocrine Carcinoma: A Case Report and Literature Review

Neuroendocrine neoplasms (NENs) are rare in the head and neck region, with the larynx being the most common site. To date, nearly 700 cases of laryngeal neuroendocrine carcinoma (NEC) have been reported in the literature, with an estimated incidence as low as 0.23%. This type of cancer is more preva...

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Main Authors: Renda Alhabib, Chaker Zaidi, Abdulrahman Alfryyan, Hanan Albenayyan, Ibrahim Alotain
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Case Reports in Oncological Medicine
Online Access:http://dx.doi.org/10.1155/2024/6844193
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author Renda Alhabib
Chaker Zaidi
Abdulrahman Alfryyan
Hanan Albenayyan
Ibrahim Alotain
author_facet Renda Alhabib
Chaker Zaidi
Abdulrahman Alfryyan
Hanan Albenayyan
Ibrahim Alotain
author_sort Renda Alhabib
collection DOAJ
description Neuroendocrine neoplasms (NENs) are rare in the head and neck region, with the larynx being the most common site. To date, nearly 700 cases of laryngeal neuroendocrine carcinoma (NEC) have been reported in the literature, with an estimated incidence as low as 0.23%. This type of cancer is more prevalent among men aged 50–83 who are heavy smokers. NENs encompass paragangliomas and epithelial neoplasms. The latter categories include neuroendocrine tumors, or typical carcinoids, and NECs, or atypical carcinoids. Due to their nonspecific and often misleading presentation, and given the rarity of this condition, optimal management lacks standardization. Treatment typically involves a combination of surgery, chemotherapy, and radiotherapy. We present a case of supraglottic laryngeal NEC in a 61-year-old female nonsmoker. The patient underwent endoscopic excision followed by adjuvant radiotherapy.
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institution Kabale University
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spelling doaj-art-33519fb7dc66435490eaafac264732992025-02-03T12:05:07ZengWileyCase Reports in Oncological Medicine2090-67142024-01-01202410.1155/2024/6844193Supraglottic Neuroendocrine Carcinoma: A Case Report and Literature ReviewRenda Alhabib0Chaker Zaidi1Abdulrahman Alfryyan2Hanan Albenayyan3Ibrahim Alotain4Radiation OncologyRadiation OncologyImam Abdulrahman Bin Faisal UniversityGeneral Pediatrics DepartmentRadiation OncologyNeuroendocrine neoplasms (NENs) are rare in the head and neck region, with the larynx being the most common site. To date, nearly 700 cases of laryngeal neuroendocrine carcinoma (NEC) have been reported in the literature, with an estimated incidence as low as 0.23%. This type of cancer is more prevalent among men aged 50–83 who are heavy smokers. NENs encompass paragangliomas and epithelial neoplasms. The latter categories include neuroendocrine tumors, or typical carcinoids, and NECs, or atypical carcinoids. Due to their nonspecific and often misleading presentation, and given the rarity of this condition, optimal management lacks standardization. Treatment typically involves a combination of surgery, chemotherapy, and radiotherapy. We present a case of supraglottic laryngeal NEC in a 61-year-old female nonsmoker. The patient underwent endoscopic excision followed by adjuvant radiotherapy.http://dx.doi.org/10.1155/2024/6844193
spellingShingle Renda Alhabib
Chaker Zaidi
Abdulrahman Alfryyan
Hanan Albenayyan
Ibrahim Alotain
Supraglottic Neuroendocrine Carcinoma: A Case Report and Literature Review
Case Reports in Oncological Medicine
title Supraglottic Neuroendocrine Carcinoma: A Case Report and Literature Review
title_full Supraglottic Neuroendocrine Carcinoma: A Case Report and Literature Review
title_fullStr Supraglottic Neuroendocrine Carcinoma: A Case Report and Literature Review
title_full_unstemmed Supraglottic Neuroendocrine Carcinoma: A Case Report and Literature Review
title_short Supraglottic Neuroendocrine Carcinoma: A Case Report and Literature Review
title_sort supraglottic neuroendocrine carcinoma a case report and literature review
url http://dx.doi.org/10.1155/2024/6844193
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AT abdulrahmanalfryyan supraglotticneuroendocrinecarcinomaacasereportandliteraturereview
AT hananalbenayyan supraglotticneuroendocrinecarcinomaacasereportandliteraturereview
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