Cardiovascular Disease Risk Factors in the Native American Population
Native Americans are disproportionately affected by cardiovascular disease in comparison with other racial and ethnic groups in the United States. Previous research has analyzed risk factors, quantified prevalence rates, and examined outcomes of cardiovascular disease in Native Americans, yet few st...
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| Format: | Article |
| Language: | English |
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MDPI AG
2025-01-01
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| Series: | Journal of Cardiovascular Development and Disease |
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| Online Access: | https://www.mdpi.com/2308-3425/12/1/27 |
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| author | Krista Goerger Karla Abbott Mark K. Larson Michael Holinstat |
| author_facet | Krista Goerger Karla Abbott Mark K. Larson Michael Holinstat |
| author_sort | Krista Goerger |
| collection | DOAJ |
| description | Native Americans are disproportionately affected by cardiovascular disease in comparison with other racial and ethnic groups in the United States. Previous research has analyzed risk factors, quantified prevalence rates, and examined outcomes of cardiovascular disease in Native Americans, yet few studies have considered the role of societal and psychological factors on the increased burden of cardiovascular disease in Native Americans. Modifiable risk factors for cardiovascular disease, including poor nutrition, reduced physical activity, obesity, and increased substance use, are exacerbated in Native American communities due to cultural and historical factors. Further, Native Americans have endured historical trauma and continue to experience additional financial and healthcare stressors, resulting in increased levels of chronic stress. Chronic activation of stress responses through the hypothalamic–pituitary–adrenal and autonomic nervous system increases inflammation and cardiovascular dysfunction resulting in an increased risk for cardiovascular disease. Therefore, it is critical to examine the connection between these stressors and the cardiovascular health disparities in Native American communities to create effective strategies to improve health outcomes. |
| format | Article |
| id | doaj-art-33498c56c8ac4960a1802fe31f0f6165 |
| institution | Kabale University |
| issn | 2308-3425 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Cardiovascular Development and Disease |
| spelling | doaj-art-33498c56c8ac4960a1802fe31f0f61652025-01-24T13:36:02ZengMDPI AGJournal of Cardiovascular Development and Disease2308-34252025-01-011212710.3390/jcdd12010027Cardiovascular Disease Risk Factors in the Native American PopulationKrista Goerger0Karla Abbott1Mark K. Larson2Michael Holinstat3Department of Pharmacology, University of Michigan, Ann Arbor, MI 48109, USANursing Department, Augustana University, Sioux Falls, SD 57197, USABiology Department, Augustana University, Sioux Falls, SD 57197, USADepartment of Pharmacology, University of Michigan, Ann Arbor, MI 48109, USANative Americans are disproportionately affected by cardiovascular disease in comparison with other racial and ethnic groups in the United States. Previous research has analyzed risk factors, quantified prevalence rates, and examined outcomes of cardiovascular disease in Native Americans, yet few studies have considered the role of societal and psychological factors on the increased burden of cardiovascular disease in Native Americans. Modifiable risk factors for cardiovascular disease, including poor nutrition, reduced physical activity, obesity, and increased substance use, are exacerbated in Native American communities due to cultural and historical factors. Further, Native Americans have endured historical trauma and continue to experience additional financial and healthcare stressors, resulting in increased levels of chronic stress. Chronic activation of stress responses through the hypothalamic–pituitary–adrenal and autonomic nervous system increases inflammation and cardiovascular dysfunction resulting in an increased risk for cardiovascular disease. Therefore, it is critical to examine the connection between these stressors and the cardiovascular health disparities in Native American communities to create effective strategies to improve health outcomes.https://www.mdpi.com/2308-3425/12/1/27cardiovascular diseaseNative AmericanAmerican Indianunder-representedchronic stress |
| spellingShingle | Krista Goerger Karla Abbott Mark K. Larson Michael Holinstat Cardiovascular Disease Risk Factors in the Native American Population Journal of Cardiovascular Development and Disease cardiovascular disease Native American American Indian under-represented chronic stress |
| title | Cardiovascular Disease Risk Factors in the Native American Population |
| title_full | Cardiovascular Disease Risk Factors in the Native American Population |
| title_fullStr | Cardiovascular Disease Risk Factors in the Native American Population |
| title_full_unstemmed | Cardiovascular Disease Risk Factors in the Native American Population |
| title_short | Cardiovascular Disease Risk Factors in the Native American Population |
| title_sort | cardiovascular disease risk factors in the native american population |
| topic | cardiovascular disease Native American American Indian under-represented chronic stress |
| url | https://www.mdpi.com/2308-3425/12/1/27 |
| work_keys_str_mv | AT kristagoerger cardiovasculardiseaseriskfactorsinthenativeamericanpopulation AT karlaabbott cardiovasculardiseaseriskfactorsinthenativeamericanpopulation AT markklarson cardiovasculardiseaseriskfactorsinthenativeamericanpopulation AT michaelholinstat cardiovasculardiseaseriskfactorsinthenativeamericanpopulation |