Middle Ear Metastases as the Initial Presentation of Breast Cancer Progression
Breast cancer (BC) is the most prevalent malignancy in women, and most of their deaths from BC are caused by metastases. The bone, liver, lungs, and skin are the most frequently involved organs in metastases. We report a rare case of middle ear metastasis from BC in a 67-year-old woman. The patient...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2023-07-01
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| Series: | Journal of Cancer Research and Practice |
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| Online Access: | https://journals.lww.com/10.4103/ejcrp.eJCRP-D-23-00009 |
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| author | Tzu-Chien Lin Ya-Chun Hsu Hui-Wen Chen Wei-Pang Chung* |
| author_facet | Tzu-Chien Lin Ya-Chun Hsu Hui-Wen Chen Wei-Pang Chung* |
| author_sort | Tzu-Chien Lin |
| collection | DOAJ |
| description | Breast cancer (BC) is the most prevalent malignancy in women, and most of their deaths from BC are caused by metastases. The bone, liver, lungs, and skin are the most frequently involved organs in metastases. We report a rare case of middle ear metastasis from BC in a 67-year-old woman. The patient had a curative modified radical mastectomy for her right BC 24 years ago and was treated with letrozole as a first-line therapy for the recurrent disease since 2016. After more than 5.5 years of treatment, computed tomography revealed otitis media with mastoiditis, and a granular tumor was found in the attic space and mesotympanum during the operation with the initial symptom of decreased left ear hearing. The mass was incompletely removed, and a biopsy eventually confirmed metastatic BC. There are very few case reports in the literature. Our case highlights the importance of surgical biopsy in differentiating middle ear neoplastic lesions. |
| format | Article |
| id | doaj-art-3347fa46887b4c4aa33203643beeb0c7 |
| institution | Kabale University |
| issn | 2311-3006 |
| language | English |
| publishDate | 2023-07-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Cancer Research and Practice |
| spelling | doaj-art-3347fa46887b4c4aa33203643beeb0c72025-01-23T05:07:13ZengWolters Kluwer Medknow PublicationsJournal of Cancer Research and Practice2311-30062023-07-0110311011210.4103/ejcrp.eJCRP-D-23-00009Middle Ear Metastases as the Initial Presentation of Breast Cancer ProgressionTzu-Chien LinYa-Chun HsuHui-Wen ChenWei-Pang Chung*Breast cancer (BC) is the most prevalent malignancy in women, and most of their deaths from BC are caused by metastases. The bone, liver, lungs, and skin are the most frequently involved organs in metastases. We report a rare case of middle ear metastasis from BC in a 67-year-old woman. The patient had a curative modified radical mastectomy for her right BC 24 years ago and was treated with letrozole as a first-line therapy for the recurrent disease since 2016. After more than 5.5 years of treatment, computed tomography revealed otitis media with mastoiditis, and a granular tumor was found in the attic space and mesotympanum during the operation with the initial symptom of decreased left ear hearing. The mass was incompletely removed, and a biopsy eventually confirmed metastatic BC. There are very few case reports in the literature. Our case highlights the importance of surgical biopsy in differentiating middle ear neoplastic lesions.https://journals.lww.com/10.4103/ejcrp.eJCRP-D-23-00009breast cancerhormone receptor positivemiddle earrare metastasis |
| spellingShingle | Tzu-Chien Lin Ya-Chun Hsu Hui-Wen Chen Wei-Pang Chung* Middle Ear Metastases as the Initial Presentation of Breast Cancer Progression Journal of Cancer Research and Practice breast cancer hormone receptor positive middle ear rare metastasis |
| title | Middle Ear Metastases as the Initial Presentation of Breast Cancer Progression |
| title_full | Middle Ear Metastases as the Initial Presentation of Breast Cancer Progression |
| title_fullStr | Middle Ear Metastases as the Initial Presentation of Breast Cancer Progression |
| title_full_unstemmed | Middle Ear Metastases as the Initial Presentation of Breast Cancer Progression |
| title_short | Middle Ear Metastases as the Initial Presentation of Breast Cancer Progression |
| title_sort | middle ear metastases as the initial presentation of breast cancer progression |
| topic | breast cancer hormone receptor positive middle ear rare metastasis |
| url | https://journals.lww.com/10.4103/ejcrp.eJCRP-D-23-00009 |
| work_keys_str_mv | AT tzuchienlin middleearmetastasesastheinitialpresentationofbreastcancerprogression AT yachunhsu middleearmetastasesastheinitialpresentationofbreastcancerprogression AT huiwenchen middleearmetastasesastheinitialpresentationofbreastcancerprogression AT weipangchung middleearmetastasesastheinitialpresentationofbreastcancerprogression |