Cell fusion as a driver of metastasis: re-evaluating an old hypothesis in the age of cancer heterogeneity

Numerous studies have investigated the molecular mechanisms and signalling pathways underlying cancer metastasis, as there is still no effective treatment for this terminal stage of the disease. However, the exact processes that enable primary cancer cells to acquire a metastatic phenotype remain un...

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Bibliographic Details
Main Authors: Eduardo López-Collazo, Laura Hurtado-Navarro
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1524781/full
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