Cognitive Impairment in Heart Failure

Cognitive impairment (CI) is increasingly recognized as a common adverse consequence of heart failure (HF). Although the exact mechanisms remain unclear, microembolism, chronic or intermittent cerebral hypoperfusion, and/or impaired cerebral vessel reactivity that lead to cerebral hypoxia and ischem...

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Main Authors: Efthimios Dardiotis, Gregory Giamouzis, Dimos Mastrogiannis, Christina Vogiatzi, John Skoularigis, Filippos Triposkiadis, Georgios M. Hadjigeorgiou
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Cardiology Research and Practice
Online Access:http://dx.doi.org/10.1155/2012/595821
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author Efthimios Dardiotis
Gregory Giamouzis
Dimos Mastrogiannis
Christina Vogiatzi
John Skoularigis
Filippos Triposkiadis
Georgios M. Hadjigeorgiou
author_facet Efthimios Dardiotis
Gregory Giamouzis
Dimos Mastrogiannis
Christina Vogiatzi
John Skoularigis
Filippos Triposkiadis
Georgios M. Hadjigeorgiou
author_sort Efthimios Dardiotis
collection DOAJ
description Cognitive impairment (CI) is increasingly recognized as a common adverse consequence of heart failure (HF). Although the exact mechanisms remain unclear, microembolism, chronic or intermittent cerebral hypoperfusion, and/or impaired cerebral vessel reactivity that lead to cerebral hypoxia and ischemic brain damage seem to underlie the development of CI in HF. Cognitive decline in HF is characterized by deficits in one or more cognition domains, including attention, memory, executive function, and psychomotor speed. These deficits may affect patients’ decision-making capacity and interfere with their ability to comply with treatment requirements, recognize and self-manage disease worsening symptoms. CI may have fluctuations in severity over time, improve with effective HF treatment or progress to dementia. CI is independently associated with disability, mortality, and decreased quality of life of HF patients. It is essential therefore for health professionals in their routine evaluations of HF patients to become familiar with assessment of cognitive performance using standardized screening instruments. Future studies should focus on elucidating the mechanisms that underlie CI in HF and establishing preventive strategies and treatment approaches.
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series Cardiology Research and Practice
spelling doaj-art-332c9fe544174418980d9c55a50b30112025-02-03T05:53:33ZengWileyCardiology Research and Practice2090-80162090-05972012-01-01201210.1155/2012/595821595821Cognitive Impairment in Heart FailureEfthimios Dardiotis0Gregory Giamouzis1Dimos Mastrogiannis2Christina Vogiatzi3John Skoularigis4Filippos Triposkiadis5Georgios M. Hadjigeorgiou6Department of Neurology, University of Thessaly, University Hospital of Larissa, P.O. Box 1400, Larissa, GreeceDepartment of Cardiology, University of Thessaly, University Hospital of Larissa, Larissa, GreeceTEI of Lamia, Lamia, GreeceDepartment of Neurology, University of Thessaly, University Hospital of Larissa, P.O. Box 1400, Larissa, GreeceDepartment of Cardiology, University of Thessaly, University Hospital of Larissa, Larissa, GreeceDepartment of Cardiology, University of Thessaly, University Hospital of Larissa, Larissa, GreeceDepartment of Neurology, University of Thessaly, University Hospital of Larissa, P.O. Box 1400, Larissa, GreeceCognitive impairment (CI) is increasingly recognized as a common adverse consequence of heart failure (HF). Although the exact mechanisms remain unclear, microembolism, chronic or intermittent cerebral hypoperfusion, and/or impaired cerebral vessel reactivity that lead to cerebral hypoxia and ischemic brain damage seem to underlie the development of CI in HF. Cognitive decline in HF is characterized by deficits in one or more cognition domains, including attention, memory, executive function, and psychomotor speed. These deficits may affect patients’ decision-making capacity and interfere with their ability to comply with treatment requirements, recognize and self-manage disease worsening symptoms. CI may have fluctuations in severity over time, improve with effective HF treatment or progress to dementia. CI is independently associated with disability, mortality, and decreased quality of life of HF patients. It is essential therefore for health professionals in their routine evaluations of HF patients to become familiar with assessment of cognitive performance using standardized screening instruments. Future studies should focus on elucidating the mechanisms that underlie CI in HF and establishing preventive strategies and treatment approaches.http://dx.doi.org/10.1155/2012/595821
spellingShingle Efthimios Dardiotis
Gregory Giamouzis
Dimos Mastrogiannis
Christina Vogiatzi
John Skoularigis
Filippos Triposkiadis
Georgios M. Hadjigeorgiou
Cognitive Impairment in Heart Failure
Cardiology Research and Practice
title Cognitive Impairment in Heart Failure
title_full Cognitive Impairment in Heart Failure
title_fullStr Cognitive Impairment in Heart Failure
title_full_unstemmed Cognitive Impairment in Heart Failure
title_short Cognitive Impairment in Heart Failure
title_sort cognitive impairment in heart failure
url http://dx.doi.org/10.1155/2012/595821
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