Frailty and cognitive impairment among community-dwelling elderly Fragilidade e alteração cognitiva em idosos comunitários

<p id="para1">The aim was to evaluate associations between frailty status and cognitive decline and the incidence of cognitive impairment over 12-month period. Two hundred seven older adults were assessed. Frailty was defined as having at least three of the following criteria: weight...

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Main Authors: Mariana Asmar Alencar, João Marcos Domingues Dias, Luisa Costa Figueiredo, Rosângela Corrêa Dias
Format: Article
Language:English
Published: Thieme Revinter Publicações 2013-06-01
Series:Arquivos de Neuro-Psiquiatria
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2013000600362
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Summary:<p id="para1">The aim was to evaluate associations between frailty status and cognitive decline and the incidence of cognitive impairment over 12-month period. Two hundred seven older adults were assessed. Frailty was defined as having at least three of the following criteria: weight loss, weakness, exhaustion, slowness, and low level of activity. Cognitive decline was assessed using the Mini Mental State Examination (MMSE) and Clinical Dementia Rating Scale (CDR). Relative risk (RR) was calculated with a 95% confidence interval (CI). Frailty was associated with subsequent cognitive decline in 12-month when assessed using the MMSE (p=0.005; RR=4.6; 95%CI 1.93&#8211;11.2). No association was found between frailty and cognitive decline measured by the CDR (p=0.393; RR=2.1; 95%CI 0.68&#8211;6.7) or between frailty and the incidence of cognitive impairment (p=0.675; RR=1.2; 95%CI 0.18&#8211;8.3). These findings reveal an association between frailty and subsequent cognitive decline when measured by the MMSE, even within a short period of time.</p><br><p id="para2">O objetivo foi avaliar a associa&#231;&#227;o entre fragilidade e o decl&#237;nio cognitivo e a incid&#234;ncia de altera&#231;&#227;o cognitiva, em 12 meses. Foram avaliados 207 idosos. Fragilidade foi definida como ter pelo menos tr&#234;s dos crit&#233;rios: perda de peso, fraqueza, exaust&#227;o, lentid&#227;o e baixo n&#237;vel de atividade. O decl&#237;nio cognitivo foi avaliado pelo Mini Exame do Estado Mental (MEEM) e pela Escala Cl&#237;nica de Dem&#234;ncia (CDR). Foi calculado o risco relativo (RR) com intervalo de confian&#231;a (IC) de 95%. A fragilidade est&#225; associada a um decl&#237;nio subsequente da fun&#231;&#227;o cognitiva em 12 meses, quando medida pelo MEEM (p=0,005; RR=4,6; IC95% 1,93&#8211;11,2). N&#227;o foi verificada associa&#231;&#227;o entre fragilidade e o decl&#237;nio da fun&#231;&#227;o cognitiva pela CDR (p=0,393; RR=2,1; IC95% 0,68&#8211;6,7) e entre a fragilidade e a incid&#234;ncia da altera&#231;&#227;o cognitiva (p=0,675; RR=1,2; IC95% 0,18&#8211;8,3). Este estudo mostrou que, mesmo em um per&#237;odo curto, existe associa&#231;&#227;o entre a fragilidade e um decl&#237;nio subsequente da fun&#231;&#227;o cognitiva, quando medida pelo MEEM.</p>
ISSN:0004-282X
1678-4227