Simple Spectrophotometric Method for Determination of Paroxetine in Tablets Using 1,2-Naphthoquinone-4-Sulphonate as a Chromogenic Reagent

Simple Spectrophotometric Method for Determination of Paroxetine in Tablets Using 1,2-Naphthoquinone-4-Sulphonate as a Chromogenic Reagent

Simple and rapid spectrophotometric method has been developed and validated for the determination of paroxetine (PRX) in tablets. The proposed method was based on nucleophilic substitution reaction of PRX with 1,2-naphthoquinone-4-sulphonate (NQS) in an alkaline medium to form an orange-colored prod...

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Bibliographic Details
Main Authors: Ibrahim A. Darwish, Heba H. Abdine, Sawsan M. Amer, Lama I. Al-Rayes
Format: Article
Language:English
Published: Wiley 2009-01-01
Series:International Journal of Analytical Chemistry
Online Access:http://dx.doi.org/10.1155/2009/237601
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