Endoscopic and immunohistochemical aspects in an inverted papilloma with unilateral total obstruction of the nasal fossa
An inverted papilloma is a medical condition in which epithelial cells placed on the surface grow in depth into the underlying supporting tissue. The case of a 68-year-old man with a 6-month history of right-sided complete nasal obstruction, who was referred to the ENT Department of our hospital...
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MDPI AG
2024-10-01
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| Series: | Journal of Mind and Medical Sciences |
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| Online Access: | https://scholar.valpo.edu/cgi/viewcontent.cgi?article=1508&context=jmms |
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| author | Irina Enache Florin Anghelina Mircea-Sorin Ciolofan Carmen Aurelia Mogoantă Alex Emilian Stepan Ioana-Cristina Vîlcea Cosmin Vasile Obleagă Andrei Osman |
| author_facet | Irina Enache Florin Anghelina Mircea-Sorin Ciolofan Carmen Aurelia Mogoantă Alex Emilian Stepan Ioana-Cristina Vîlcea Cosmin Vasile Obleagă Andrei Osman |
| author_sort | Irina Enache |
| collection | DOAJ |
| description | An inverted papilloma is a medical condition in which epithelial cells
placed on the surface grow in depth into the underlying supporting tissue.
The case of a 68-year-old man with a 6-month history of right-sided
complete nasal obstruction, who was referred to the ENT Department of
our hospital, is presented. The associated symptoms were represented by
repeated epistaxis, rhinorrhea and anosmia. From a clinical point of view,
a polypous reddish-gray irregular mass, with cauliflower-like appearance,
has been described. The formation was friable, richly vascularized, and
with minor bleeding on light touch. The patient was diagnosed with
inverted papilloma which was treated by endoscopic surgery. By analyzing
the clinical, histochemical and immunohistochemical aspects of this case,
the cause of tumor growth and its potential for malignant transformation
were established. Many particularities are presented in this article:
increased regional aggressiveness, its ethmoidal sinus origin, specific
symptomatology, paraclinical examinations, all of which were useful in
choosing a customized therapy and follow-up program.
|
| format | Article |
| id | doaj-art-32eff2d3804f44a0b4b5038b51b39ab3 |
| institution | DOAJ |
| issn | 2392-7674 |
| language | English |
| publishDate | 2024-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Mind and Medical Sciences |
| spelling | doaj-art-32eff2d3804f44a0b4b5038b51b39ab32025-08-20T03:18:44ZengMDPI AGJournal of Mind and Medical Sciences2392-76742024-10-0111254154610.22543/2392-7674.1508Endoscopic and immunohistochemical aspects in an inverted papilloma with unilateral total obstruction of the nasal fossaIrina Enache0Florin Anghelina1Mircea-Sorin Ciolofan2Carmen Aurelia Mogoantă3Alex Emilian Stepan4Ioana-Cristina Vîlcea5Cosmin Vasile Obleagă6Andrei Osman7Craiova University of Medicine and Pharmacy, Faculty of Medicine, Department of Anatomy and Embryology, Craiova, RomaniaCraiova University of Medicine and Pharmacy, Faculty of Medicine, Department of ENT, Craiova, RomaniaCraiova University of Medicine and Pharmacy, Faculty of Medicine, Department of ENT, Craiova, RomaniaCraiova University of Medicine and Pharmacy, Faculty of Medicine, Department of ENT, Craiova, RomaniaCraiova University of Medicine and Pharmacy, Faculty of Medicine, Department of Pathology, Craiova, RomaniaCraiova University of Medicine and Pharmacy, Faculty of Medicine, Department of Pathology, Craiova, RomaniaCraiova University of Medicine and Pharmacy, Faculty of Medicine, Department of Surgery, Craiova, RomaniaCraiova University of Medicine and Pharmacy, Faculty of Medicine, Department of Anatomy and Embryology, Craiova, RomaniaAn inverted papilloma is a medical condition in which epithelial cells placed on the surface grow in depth into the underlying supporting tissue. The case of a 68-year-old man with a 6-month history of right-sided complete nasal obstruction, who was referred to the ENT Department of our hospital, is presented. The associated symptoms were represented by repeated epistaxis, rhinorrhea and anosmia. From a clinical point of view, a polypous reddish-gray irregular mass, with cauliflower-like appearance, has been described. The formation was friable, richly vascularized, and with minor bleeding on light touch. The patient was diagnosed with inverted papilloma which was treated by endoscopic surgery. By analyzing the clinical, histochemical and immunohistochemical aspects of this case, the cause of tumor growth and its potential for malignant transformation were established. Many particularities are presented in this article: increased regional aggressiveness, its ethmoidal sinus origin, specific symptomatology, paraclinical examinations, all of which were useful in choosing a customized therapy and follow-up program. https://scholar.valpo.edu/cgi/viewcontent.cgi?article=1508&context=jmmsinverted papillomaendoscopicimmunohistochemistrymalignant transformationregional aggressivity |
| spellingShingle | Irina Enache Florin Anghelina Mircea-Sorin Ciolofan Carmen Aurelia Mogoantă Alex Emilian Stepan Ioana-Cristina Vîlcea Cosmin Vasile Obleagă Andrei Osman Endoscopic and immunohistochemical aspects in an inverted papilloma with unilateral total obstruction of the nasal fossa Journal of Mind and Medical Sciences inverted papilloma endoscopic immunohistochemistry malignant transformation regional aggressivity |
| title | Endoscopic and immunohistochemical aspects in an inverted papilloma with unilateral total obstruction of the nasal fossa |
| title_full | Endoscopic and immunohistochemical aspects in an inverted papilloma with unilateral total obstruction of the nasal fossa |
| title_fullStr | Endoscopic and immunohistochemical aspects in an inverted papilloma with unilateral total obstruction of the nasal fossa |
| title_full_unstemmed | Endoscopic and immunohistochemical aspects in an inverted papilloma with unilateral total obstruction of the nasal fossa |
| title_short | Endoscopic and immunohistochemical aspects in an inverted papilloma with unilateral total obstruction of the nasal fossa |
| title_sort | endoscopic and immunohistochemical aspects in an inverted papilloma with unilateral total obstruction of the nasal fossa |
| topic | inverted papilloma endoscopic immunohistochemistry malignant transformation regional aggressivity |
| url | https://scholar.valpo.edu/cgi/viewcontent.cgi?article=1508&context=jmms |
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