Iatrogenic Pulmonary Nodule in a Heart Transplant Recipient

A 58-year-old female with a history of non-Hodgkin lymphoma and end-stage nonischemic cardiomyopathy from Adriamycin toxicity underwent orthotic heart transplantation during June 2013. She developed shortness of breath in September 2013 and was suspected to have invasive pulmonary aspergillosis. A f...

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Main Authors: Atul C. Mehta, Juan Wang, Jarmanjeet Singh, Joseph Cicenia
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Case Reports in Pulmonology
Online Access:http://dx.doi.org/10.1155/2014/546209
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author Atul C. Mehta
Juan Wang
Jarmanjeet Singh
Joseph Cicenia
author_facet Atul C. Mehta
Juan Wang
Jarmanjeet Singh
Joseph Cicenia
author_sort Atul C. Mehta
collection DOAJ
description A 58-year-old female with a history of non-Hodgkin lymphoma and end-stage nonischemic cardiomyopathy from Adriamycin toxicity underwent orthotic heart transplantation during June 2013. She developed shortness of breath in September 2013 and was suspected to have invasive pulmonary aspergillosis. A flexible bronchoscopy (FB) with a transbronchial biopsy (TBBx) was performed. She was found to have a focal lung nodule in the same location at the site of the TBBx on day 13 after the FB. Spontaneous resolution of the nodule was confirmed on the computed tomography (CT) scan of chest performed at 3 months. We believe that this nodule was as a consequence of the TBBx. Formation of a peripheral pulmonary nodule (PPN) following a TBBx is occasionally encountered among the recipients of the lung transplantation. To our knowledge, this is the first case of TBBx producing a pulmonary nodule in a heart transplant recipient. Physicians caring for the patients with heart transplantation should be cognizant of the iatrogenic nature of such nodule to avoid unnecessary diagnostic work-up.
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spelling doaj-art-32efb29652454add8eae7d5f7556dd762025-02-03T05:45:58ZengWileyCase Reports in Pulmonology2090-68462090-68542014-01-01201410.1155/2014/546209546209Iatrogenic Pulmonary Nodule in a Heart Transplant RecipientAtul C. Mehta0Juan Wang1Jarmanjeet Singh2Joseph Cicenia3Department of Pulmonary Medicine, Respiratory Institute, Cleveland Clinic, Cleveland, OH 44195, USADepartment of Pulmonary Diseases, Tiantan Hospital, Beijing 100050, ChinaMaharaja Agrasen Medical College, Agroha 125047, IndiaDepartment of Pulmonary Medicine, Respiratory Institute, Cleveland Clinic, Cleveland, OH 44195, USAA 58-year-old female with a history of non-Hodgkin lymphoma and end-stage nonischemic cardiomyopathy from Adriamycin toxicity underwent orthotic heart transplantation during June 2013. She developed shortness of breath in September 2013 and was suspected to have invasive pulmonary aspergillosis. A flexible bronchoscopy (FB) with a transbronchial biopsy (TBBx) was performed. She was found to have a focal lung nodule in the same location at the site of the TBBx on day 13 after the FB. Spontaneous resolution of the nodule was confirmed on the computed tomography (CT) scan of chest performed at 3 months. We believe that this nodule was as a consequence of the TBBx. Formation of a peripheral pulmonary nodule (PPN) following a TBBx is occasionally encountered among the recipients of the lung transplantation. To our knowledge, this is the first case of TBBx producing a pulmonary nodule in a heart transplant recipient. Physicians caring for the patients with heart transplantation should be cognizant of the iatrogenic nature of such nodule to avoid unnecessary diagnostic work-up.http://dx.doi.org/10.1155/2014/546209
spellingShingle Atul C. Mehta
Juan Wang
Jarmanjeet Singh
Joseph Cicenia
Iatrogenic Pulmonary Nodule in a Heart Transplant Recipient
Case Reports in Pulmonology
title Iatrogenic Pulmonary Nodule in a Heart Transplant Recipient
title_full Iatrogenic Pulmonary Nodule in a Heart Transplant Recipient
title_fullStr Iatrogenic Pulmonary Nodule in a Heart Transplant Recipient
title_full_unstemmed Iatrogenic Pulmonary Nodule in a Heart Transplant Recipient
title_short Iatrogenic Pulmonary Nodule in a Heart Transplant Recipient
title_sort iatrogenic pulmonary nodule in a heart transplant recipient
url http://dx.doi.org/10.1155/2014/546209
work_keys_str_mv AT atulcmehta iatrogenicpulmonarynoduleinahearttransplantrecipient
AT juanwang iatrogenicpulmonarynoduleinahearttransplantrecipient
AT jarmanjeetsingh iatrogenicpulmonarynoduleinahearttransplantrecipient
AT josephcicenia iatrogenicpulmonarynoduleinahearttransplantrecipient