Mutational accumulation drives pathway dysregulation to predict glioma patient survival
Abstract Previous studies majorly focused on the role of driver gene variation in the occurrence, development and treatment of glioma. Here, we revealed the effect of signaling pathway abnormality by accumulated genetic mutations on patient survival and explored potential mechanism in glioma. We fou...
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| Main Authors: | Mengjiao Wan, Caiping Zhuang, Wei Li, Rongrong Yan, Wen Chen, Jing Cheng, Chengjin Yue, Lin Chen, Yingyao Quan |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
|
| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-12346-3 |
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