A self‐propagating, barcoded transposon system for the dynamic rewiring of genomic networks
Abstract In bacteria, natural transposon mobilization can drive adaptive genomic rearrangements. Here, we build on this capability and develop an inducible, self‐propagating transposon platform for continuous genome‐wide mutagenesis and the dynamic rewiring of gene networks in bacteria. We first use...
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| Main Authors: | Max A English, Miguel A Alcantar, James J Collins |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2023-03-01
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| Series: | Molecular Systems Biology |
| Subjects: | |
| Online Access: | https://doi.org/10.15252/msb.202211398 |
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