Comparative analysis of machine learning approaches for predicting the risk of vaginal laxity

Abstract This study develops predictive models for Chinese female patients with VL utilizing machine learning techniques. The aim is to create an effective model that can assist in clinical diagnosis and treatment of vaginal relaxation, thereby enhancing women’s pelvic floor health. In total, 1184 w...

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Main Authors: Hongguo Zhao, Peng Liu, Fei Chen, Mengjuan Wang, Jiaxi Liu, Xiling Fu, Hang Yu, Manman Nai, Lei Li, Xinbin Li
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-86931-x
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author Hongguo Zhao
Peng Liu
Fei Chen
Mengjuan Wang
Jiaxi Liu
Xiling Fu
Hang Yu
Manman Nai
Lei Li
Xinbin Li
author_facet Hongguo Zhao
Peng Liu
Fei Chen
Mengjuan Wang
Jiaxi Liu
Xiling Fu
Hang Yu
Manman Nai
Lei Li
Xinbin Li
author_sort Hongguo Zhao
collection DOAJ
description Abstract This study develops predictive models for Chinese female patients with VL utilizing machine learning techniques. The aim is to create an effective model that can assist in clinical diagnosis and treatment of vaginal relaxation, thereby enhancing women’s pelvic floor health. In total, 1184 women with VL have been randomly selected and categorized into groups using the finger measurement method. Among them, there are 383 cases of mild VL, 405 cases of moderate VL, and 396 cases of severe VL. Concurrently, 396 healthy women without VL who underwent routine health examinations have been chosen at random and assigned to the non-VL group. Based on 1580 cases, we have established LightGBM, Random Forest, XGBoost, and AdaBoost models based on training dataset using 5-fold cross-validation and GridSearch, and analyzed the performance of the models on the hold-out test dataset. The confusion matrix, precision, recall, F1 score, overall accuracy, and ROC curve of the models on the hold-out test dataset are compared. The overall accuracy of LightGBM model, RF model, XGBoost model, and AdaBoost model are 0.8987, 0.8987, 0.8987, and 0.8457, respectively. The average AUC of LightGBM model is 0.976, the one of RF model is 0.9763, the one of XGBoost model is 0.9775, and the one of AdaBoost model is 0.928. The XGBoost model has the more comprehensive and reasonable performance among the four prediction models, which can accurately distinguish between healthy, mild VL, as well as moderate VL and severe VL, which can assist doctors in diagnosing persons’ conditions more accurately, devising personalized treatment plans, avoiding unnecessary surgeries, reducing persons’ psychological stress, improving patient compliance and treatment outcomes, thus enhancing overall treatment results.
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institution Kabale University
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language English
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spelling doaj-art-32b6fd5b310f41f3853502156b9112eb2025-01-26T12:32:19ZengNature PortfolioScientific Reports2045-23222025-01-0115111210.1038/s41598-025-86931-xComparative analysis of machine learning approaches for predicting the risk of vaginal laxityHongguo Zhao0Peng Liu1Fei Chen2Mengjuan Wang3Jiaxi Liu4Xiling Fu5Hang Yu6Manman Nai7Lei Li8Xinbin Li9The Department of Obstetrics and Gynecology, The Third Affiliated Hospital of Zhengzhou UniversityThe Department of Obstetrics and Gynecology, The Third Affiliated Hospital of Zhengzhou UniversityThe Department of Obstetrics and Gynecology, The Third Affiliated Hospital of Zhengzhou UniversityThe Department of Obstetrics and Gynecology, The Third Affiliated Hospital of Zhengzhou UniversityThe Department of Obstetrics and Gynecology, The Third Affiliated Hospital of Zhengzhou UniversityThe Department of Obstetrics and Gynecology, The Third Affiliated Hospital of Zhengzhou UniversityThe Department of Obstetrics and Gynecology, The Third Affiliated Hospital of Zhengzhou UniversityThe Department of Obstetrics and Gynecology, The Third Affiliated Hospital of Zhengzhou UniversityThe Department of Obstetrics and Gynecology, The Third Affiliated Hospital of Zhengzhou UniversitySchool of Marine Science and Technology, Northwestern Polytechnical UniversityAbstract This study develops predictive models for Chinese female patients with VL utilizing machine learning techniques. The aim is to create an effective model that can assist in clinical diagnosis and treatment of vaginal relaxation, thereby enhancing women’s pelvic floor health. In total, 1184 women with VL have been randomly selected and categorized into groups using the finger measurement method. Among them, there are 383 cases of mild VL, 405 cases of moderate VL, and 396 cases of severe VL. Concurrently, 396 healthy women without VL who underwent routine health examinations have been chosen at random and assigned to the non-VL group. Based on 1580 cases, we have established LightGBM, Random Forest, XGBoost, and AdaBoost models based on training dataset using 5-fold cross-validation and GridSearch, and analyzed the performance of the models on the hold-out test dataset. The confusion matrix, precision, recall, F1 score, overall accuracy, and ROC curve of the models on the hold-out test dataset are compared. The overall accuracy of LightGBM model, RF model, XGBoost model, and AdaBoost model are 0.8987, 0.8987, 0.8987, and 0.8457, respectively. The average AUC of LightGBM model is 0.976, the one of RF model is 0.9763, the one of XGBoost model is 0.9775, and the one of AdaBoost model is 0.928. The XGBoost model has the more comprehensive and reasonable performance among the four prediction models, which can accurately distinguish between healthy, mild VL, as well as moderate VL and severe VL, which can assist doctors in diagnosing persons’ conditions more accurately, devising personalized treatment plans, avoiding unnecessary surgeries, reducing persons’ psychological stress, improving patient compliance and treatment outcomes, thus enhancing overall treatment results.https://doi.org/10.1038/s41598-025-86931-xVaginal laxityMachine learningModified Oxford muscle strength gradingPelvic floor pressure assessment
spellingShingle Hongguo Zhao
Peng Liu
Fei Chen
Mengjuan Wang
Jiaxi Liu
Xiling Fu
Hang Yu
Manman Nai
Lei Li
Xinbin Li
Comparative analysis of machine learning approaches for predicting the risk of vaginal laxity
Scientific Reports
Vaginal laxity
Machine learning
Modified Oxford muscle strength grading
Pelvic floor pressure assessment
title Comparative analysis of machine learning approaches for predicting the risk of vaginal laxity
title_full Comparative analysis of machine learning approaches for predicting the risk of vaginal laxity
title_fullStr Comparative analysis of machine learning approaches for predicting the risk of vaginal laxity
title_full_unstemmed Comparative analysis of machine learning approaches for predicting the risk of vaginal laxity
title_short Comparative analysis of machine learning approaches for predicting the risk of vaginal laxity
title_sort comparative analysis of machine learning approaches for predicting the risk of vaginal laxity
topic Vaginal laxity
Machine learning
Modified Oxford muscle strength grading
Pelvic floor pressure assessment
url https://doi.org/10.1038/s41598-025-86931-x
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