Targeted CQA analytical control strategy for commercial antibody products: Replacing ion-exchange chromatography methods for charge heterogeneity with multi-attribute monitoring

Targeted CQA analytical control strategy for commercial antibody products: Replacing ion-exchange chromatography methods for charge heterogeneity with multi-attribute monitoring

Peptide mapping with mass spectrometry (MS) is an important tool for protein characterization in the biopharmaceutical industry. Historically, peptide mapping monitors post-translational modifications (PTMs) of protein products and process intermediates during development. Multi-attribute monitoring...

Full description

Saved in:
Bibliographic Details
Main Authors: Adam R. Evans, Joseph Mulholland, Michael J. Lewis, Ping Hu
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:mAbs
Subjects:
Assay replacement
control strategy
CQA monitoring
MAM
mass spectrometry
monoclonal antibody
Online Access:https://www.tandfonline.com/doi/10.1080/19420862.2024.2341641
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items