Rituximab-Induced Coronary Vasospasm
Rituximab has improved the treatment of B-cell non-Hodgkin lymphomas. While it is generally well tolerated, serious adverse effects including infusion reactions with hemodynamic compromise and cardiac arrhythmias or ischemia are possible. We report a case of coronary vasospasm occurring during a r...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Case Reports in Hematology |
| Online Access: | http://dx.doi.org/10.1155/2012/984986 |
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| _version_ | 1832565154371338240 |
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| author | Linda Lee Vishal Kukreti |
| author_facet | Linda Lee Vishal Kukreti |
| author_sort | Linda Lee |
| collection | DOAJ |
| description | Rituximab has improved the treatment of B-cell non-Hodgkin lymphomas. While it is generally well tolerated, serious adverse effects including infusion reactions with hemodynamic compromise and cardiac arrhythmias or ischemia are possible. We report a case of coronary vasospasm occurring during a rituximab infusion in a patient with minimal tumour burden and who had no cardiac risk factors. This case highlights that determination of the cause of ischemia is important and may identify some patients who can be successfully rechallenged. |
| format | Article |
| id | doaj-art-329c79760cfc4becacca8886bea3e157 |
| institution | Kabale University |
| issn | 2090-6560 2090-6579 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Hematology |
| spelling | doaj-art-329c79760cfc4becacca8886bea3e1572025-02-03T01:09:02ZengWileyCase Reports in Hematology2090-65602090-65792012-01-01201210.1155/2012/984986984986Rituximab-Induced Coronary VasospasmLinda Lee0Vishal Kukreti1Department of Oncology, Niagara Health System, St. Catharines, ON, L2R 2Z7, CanadaDepartment of Medical Oncology & Hematology, Princess Margaret Hospital, Room 5-227, 610 University Avenue, Toronto, ON, M5G 2M9, CanadaRituximab has improved the treatment of B-cell non-Hodgkin lymphomas. While it is generally well tolerated, serious adverse effects including infusion reactions with hemodynamic compromise and cardiac arrhythmias or ischemia are possible. We report a case of coronary vasospasm occurring during a rituximab infusion in a patient with minimal tumour burden and who had no cardiac risk factors. This case highlights that determination of the cause of ischemia is important and may identify some patients who can be successfully rechallenged.http://dx.doi.org/10.1155/2012/984986 |
| spellingShingle | Linda Lee Vishal Kukreti Rituximab-Induced Coronary Vasospasm Case Reports in Hematology |
| title | Rituximab-Induced Coronary Vasospasm |
| title_full | Rituximab-Induced Coronary Vasospasm |
| title_fullStr | Rituximab-Induced Coronary Vasospasm |
| title_full_unstemmed | Rituximab-Induced Coronary Vasospasm |
| title_short | Rituximab-Induced Coronary Vasospasm |
| title_sort | rituximab induced coronary vasospasm |
| url | http://dx.doi.org/10.1155/2012/984986 |
| work_keys_str_mv | AT lindalee rituximabinducedcoronaryvasospasm AT vishalkukreti rituximabinducedcoronaryvasospasm |