Osteomyelitis and Osteonecrosis in Inflammatory Bowel Disease

Osteomyelitis and osteonecrosis are skeletal disorders seen in patients with inflammatory bowel disease (IBD). Osteomyelitis usually occurs in the pelvic bones, especially in complicated C...

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Main Author: Hugh J Freeman
Format: Article
Language:English
Published: Wiley 1997-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/1997/953252
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author Hugh J Freeman
author_facet Hugh J Freeman
author_sort Hugh J Freeman
collection DOAJ
description Osteomyelitis and osteonecrosis are skeletal disorders seen in patients with inflammatory bowel disease (IBD). Osteomyelitis usually occurs in the pelvic bones, especially in complicated Crohn's disease, presumably by direct extension from a pelvic inflammatory mass, abscess or fistulous tract. Diagnosis of osteomyelitis may be difficult and can lead to spinal extension of the septic process with a resultant neurological deficit, including paraplegia. Osteonecrosis or avascular necrosis has been reported in patients with either ulcerative colitis or Crohn's disease, often, but not exclusively, during or following steroid treatment. The disease is often multifocal, but its natural history is unknown, especially if diagnosed early with modern imaging methods, such as magnetic resonance. In IBD patients, the relationship between osteonecrosis and steroid use is unknown. An adverse steroid effect on bones, especially the femoral heads, may develop in some patients with IBD but, to date, this hypothesis remains unproven. Critical evaluation of published data reveals no consistent association between osteonecrosis and steroid treatment in IBD patients.
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spelling doaj-art-329547ef23834d57a016f87bc6b7c6672025-02-03T05:49:42ZengWileyCanadian Journal of Gastroenterology0835-79001997-01-0111760160610.1155/1997/953252Osteomyelitis and Osteonecrosis in Inflammatory Bowel DiseaseHugh J FreemanOsteomyelitis and osteonecrosis are skeletal disorders seen in patients with inflammatory bowel disease (IBD). Osteomyelitis usually occurs in the pelvic bones, especially in complicated Crohn's disease, presumably by direct extension from a pelvic inflammatory mass, abscess or fistulous tract. Diagnosis of osteomyelitis may be difficult and can lead to spinal extension of the septic process with a resultant neurological deficit, including paraplegia. Osteonecrosis or avascular necrosis has been reported in patients with either ulcerative colitis or Crohn's disease, often, but not exclusively, during or following steroid treatment. The disease is often multifocal, but its natural history is unknown, especially if diagnosed early with modern imaging methods, such as magnetic resonance. In IBD patients, the relationship between osteonecrosis and steroid use is unknown. An adverse steroid effect on bones, especially the femoral heads, may develop in some patients with IBD but, to date, this hypothesis remains unproven. Critical evaluation of published data reveals no consistent association between osteonecrosis and steroid treatment in IBD patients.http://dx.doi.org/10.1155/1997/953252
spellingShingle Hugh J Freeman
Osteomyelitis and Osteonecrosis in Inflammatory Bowel Disease
Canadian Journal of Gastroenterology
title Osteomyelitis and Osteonecrosis in Inflammatory Bowel Disease
title_full Osteomyelitis and Osteonecrosis in Inflammatory Bowel Disease
title_fullStr Osteomyelitis and Osteonecrosis in Inflammatory Bowel Disease
title_full_unstemmed Osteomyelitis and Osteonecrosis in Inflammatory Bowel Disease
title_short Osteomyelitis and Osteonecrosis in Inflammatory Bowel Disease
title_sort osteomyelitis and osteonecrosis in inflammatory bowel disease
url http://dx.doi.org/10.1155/1997/953252
work_keys_str_mv AT hughjfreeman osteomyelitisandosteonecrosisininflammatoryboweldisease