Determinants of Chronic Kidney Disease among Young Adults attending a Tertiary Care Hospital in Madurai- A Case-Control Study
Introduction: As with other non-communicable diseases, chronic kidney disease (CKD) also is in a way at the top among the younger population. Apart from diabetes, hypertension, old age, family history of CKD other risk factors like smoking, alcohol, pesticide exposure, heavy metals also made them vu...
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Indian Association of Preventive and Social Medicine
2024-12-01
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| Online Access: | https://www.healthlinejournal.org/index_pdf/559.pdf |
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| author | Sridevi PN Thirukumaran R Kannan Muthuraman A Arunkumar Yograj Priya S Hemamalini B |
| author_facet | Sridevi PN Thirukumaran R Kannan Muthuraman A Arunkumar Yograj Priya S Hemamalini B |
| author_sort | Sridevi PN |
| collection | DOAJ |
| description | Introduction: As with other non-communicable diseases, chronic kidney disease (CKD) also is in a way at the top among the younger population. Apart from diabetes, hypertension, old age, family history of CKD other risk factors like smoking, alcohol, pesticide exposure, heavy metals also made them vulnerable to CKD. The focus on CKD in younger age groups is often overlooked; therefore, this study has been planned to address this gap. Objective: To determine the risk factors for chronic kidney disease among young adult patients <40
years of age. Method: An unmatched case control study was conducted in district hospital in Madurai. The study compared patients with chronic kidney disease aged under 40 (cases) from the Nephrology ward and outpatient with similar-aged controls without CKD from the Medicine ward, using routine eGFR calculations for diagnosis. The calculated sample size was 76, which was rounded up to 100 participants in both the case and control groups. Data collection was done by using semi-structured questionnaire. Univariate and
multivariate analysis were used to predict the risk factors for young CKD patients. Results: The study predicted that rural population (OR-5.236, 95% CI-2.489- 11.014), family history of CKD (OR-29.590, 95% CI- 3.351-261.243), hypertension (OR-5.005, 95% CI-2.014-12.437), history of taking alternative medicine (OR-
5.136, 95% CI-1.745-15.117), and recurrent urinary tract infection (OR-11.460, 95% CI-2.288-57.444) were significantly associated risk factors for CKD. Conclusion: This study predicted hypertension, rural population, family history of CKD, history of recurrent urinary tract infection, alcohol consumption as
significant risk factors for CKD. Hypertension, history of recurrent urinary tract infection, alcohol consumption were modifiable risk factors. By controlling these modifiable risk factors, the burden of CKD can be reduced. In addition this study predicted that, rural population was more vulnerable to CKD, so the
screening service to these populations through primary health care approach is essential. |
| format | Article |
| id | doaj-art-327c498a233f4b3cb9524746523a11a1 |
| institution | Kabale University |
| issn | 2229-337X 2320-1525 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Indian Association of Preventive and Social Medicine |
| record_format | Article |
| series | Healthline |
| spelling | doaj-art-327c498a233f4b3cb9524746523a11a12025-01-21T07:18:57ZengIndian Association of Preventive and Social MedicineHealthline2229-337X2320-15252024-12-0115432933810.51957/Healthline_678_2024Determinants of Chronic Kidney Disease among Young Adults attending a Tertiary Care Hospital in Madurai- A Case-Control StudySridevi PN0Thirukumaran R 1Kannan Muthuraman A2Arunkumar Yograj3Priya S4Hemamalini B5Madurai Medical College, Madurai, IndiaMadurai Medical College, Madurai, IndiaMadurai Medical College, Madurai, IndiaMadurai Medical College, Madurai, IndiaSivagangai Medical College, Sivagangai, IndiaMadras Medical College, Madras, IndiaIntroduction: As with other non-communicable diseases, chronic kidney disease (CKD) also is in a way at the top among the younger population. Apart from diabetes, hypertension, old age, family history of CKD other risk factors like smoking, alcohol, pesticide exposure, heavy metals also made them vulnerable to CKD. The focus on CKD in younger age groups is often overlooked; therefore, this study has been planned to address this gap. Objective: To determine the risk factors for chronic kidney disease among young adult patients <40 years of age. Method: An unmatched case control study was conducted in district hospital in Madurai. The study compared patients with chronic kidney disease aged under 40 (cases) from the Nephrology ward and outpatient with similar-aged controls without CKD from the Medicine ward, using routine eGFR calculations for diagnosis. The calculated sample size was 76, which was rounded up to 100 participants in both the case and control groups. Data collection was done by using semi-structured questionnaire. Univariate and multivariate analysis were used to predict the risk factors for young CKD patients. Results: The study predicted that rural population (OR-5.236, 95% CI-2.489- 11.014), family history of CKD (OR-29.590, 95% CI- 3.351-261.243), hypertension (OR-5.005, 95% CI-2.014-12.437), history of taking alternative medicine (OR- 5.136, 95% CI-1.745-15.117), and recurrent urinary tract infection (OR-11.460, 95% CI-2.288-57.444) were significantly associated risk factors for CKD. Conclusion: This study predicted hypertension, rural population, family history of CKD, history of recurrent urinary tract infection, alcohol consumption as significant risk factors for CKD. Hypertension, history of recurrent urinary tract infection, alcohol consumption were modifiable risk factors. By controlling these modifiable risk factors, the burden of CKD can be reduced. In addition this study predicted that, rural population was more vulnerable to CKD, so the screening service to these populations through primary health care approach is essential. https://www.healthlinejournal.org/index_pdf/559.pdfcase control studychronic kidney diseaserisk factorsyoung adults |
| spellingShingle | Sridevi PN Thirukumaran R Kannan Muthuraman A Arunkumar Yograj Priya S Hemamalini B Determinants of Chronic Kidney Disease among Young Adults attending a Tertiary Care Hospital in Madurai- A Case-Control Study Healthline case control study chronic kidney disease risk factors young adults |
| title | Determinants of Chronic Kidney Disease among Young Adults attending a Tertiary Care Hospital in Madurai- A Case-Control Study |
| title_full | Determinants of Chronic Kidney Disease among Young Adults attending a Tertiary Care Hospital in Madurai- A Case-Control Study |
| title_fullStr | Determinants of Chronic Kidney Disease among Young Adults attending a Tertiary Care Hospital in Madurai- A Case-Control Study |
| title_full_unstemmed | Determinants of Chronic Kidney Disease among Young Adults attending a Tertiary Care Hospital in Madurai- A Case-Control Study |
| title_short | Determinants of Chronic Kidney Disease among Young Adults attending a Tertiary Care Hospital in Madurai- A Case-Control Study |
| title_sort | determinants of chronic kidney disease among young adults attending a tertiary care hospital in madurai a case control study |
| topic | case control study chronic kidney disease risk factors young adults |
| url | https://www.healthlinejournal.org/index_pdf/559.pdf |
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