Determination of Tropifexor in Beagle Dog Plasma by UPLC-MS/MS and Its Application in Pharmacokinetics

Determination of Tropifexor in Beagle Dog Plasma by UPLC-MS/MS and Its Application in Pharmacokinetics

The primary objective of this study was to develop and validate an efficient and accurate ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) approach as a means to detect tropifexor plasma concentrations in beagle dogs and to study its pharmacokinetic profile in beagle dog...

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Bibliographic Details
Main Authors: Yan-Ding Su, Xin-Yi Wei, Xiao-Hang Su, Ghulam Woshur, Xiao-Nan Geng, Xiang-Jun Qiu
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Journal of Analytical Methods in Chemistry
Online Access:http://dx.doi.org/10.1155/2022/2823214
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