YAP1 activates SLC2A1 transcription and augments the malignant behavior of colorectal cancer cells by activating the Wnt/β-catenin signaling pathway

YAP1 activates SLC2A1 transcription and augments the malignant behavior of colorectal cancer cells by activating the Wnt/β-catenin signaling pathway

Abstract Objective This paper examined the role of solute carrier family 2 member 1 (SLC2A1) in colorectal cancer (CRC) progression, focusing on its expression levels, functional implications, and regulatory mechanisms involving Yes-associated protein 1 (YAP1) and the Wnt signaling pathway. Methods...

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Bibliographic Details
Main Authors: Kunpeng Li, Ya-Jie Dai, Haifeng Zhang, Zhigang Zhang
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Cell Division
Subjects:
CRC
SLC2A1
YAP1
Wnt signaling pathway
Metastasis
Online Access:https://doi.org/10.1186/s13008-025-00148-y
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