Antimicrobial Resistance Associated with Mass Gatherings: A Systematic Review
Mass gatherings are associated with the spread of communicable diseases. Some studies have suggested that acquisition of antimicrobial resistance (AMR) may be associated with attendance at specific mass gatherings. This systematic review aimed to synthesise evidence on the association between attend...
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| Language: | English |
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MDPI AG
2024-12-01
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| Series: | Tropical Medicine and Infectious Disease |
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| Online Access: | https://www.mdpi.com/2414-6366/10/1/2 |
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| author | Linda Tong Pao Mohamed Tashani Catherine King Harunor Rashid Ameneh Khatami |
| author_facet | Linda Tong Pao Mohamed Tashani Catherine King Harunor Rashid Ameneh Khatami |
| author_sort | Linda Tong Pao |
| collection | DOAJ |
| description | Mass gatherings are associated with the spread of communicable diseases. Some studies have suggested that acquisition of antimicrobial resistance (AMR) may be associated with attendance at specific mass gatherings. This systematic review aimed to synthesise evidence on the association between attendance at mass gatherings and antimicrobial resistance (AMR) and assess the prevalence of AMR at mass gatherings. A literature search of the Cochrane, Medline, Scopus, and Embase databases was performed. Studies were included if they reported original data, involved mass gatherings, and reported AMR results. Of 5559 titles screened, 44 studies met the inclusion criteria, most of which (<i>n</i> = 40) involved religious mass gatherings. The heterogeneity of the studies precluded a meta-analysis, hence a narrative synthesis by organism was conducted. A significant increase in antibiotic-resistant <i>Escherichia coli</i> and <i>Klebsiella pneumoniae</i> was reported following Hajj, as was a rise in gastrointestinal carriage of extended-spectrum β-lactamase (ESBL) or carbapenemase genes. Carriage of <i>Streptococcus pneumoniae</i> isolates non-susceptible to one or more antibiotics was also shown to increase from pre-Hajj to post-Hajj. There appears to be an association between attendance at mass gatherings and the acquisition of some AMR phenotypes and genotypes in some significant human pathogens, including <i>E. coli</i> and <i>S. pneumoniae</i>. |
| format | Article |
| id | doaj-art-3269f45234854645a4bc87f15496db90 |
| institution | Kabale University |
| issn | 2414-6366 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | MDPI AG |
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| series | Tropical Medicine and Infectious Disease |
| spelling | doaj-art-3269f45234854645a4bc87f15496db902025-01-24T13:51:20ZengMDPI AGTropical Medicine and Infectious Disease2414-63662024-12-01101210.3390/tropicalmed10010002Antimicrobial Resistance Associated with Mass Gatherings: A Systematic ReviewLinda Tong Pao0Mohamed Tashani1Catherine King2Harunor Rashid3Ameneh Khatami4Sydney Children’s Hospitals Network, Westmead, NSW 2145, AustraliaThe Children’s Hospital at Westmead Clinical School, Faculty of Medicine and Health, The University of Sydney, Westmead, NSW 2145, AustraliaSydney Infectious Diseases Institute, The University of Sydney, Westmead, NSW 2145, AustraliaThe Children’s Hospital at Westmead Clinical School, Faculty of Medicine and Health, The University of Sydney, Westmead, NSW 2145, AustraliaSydney Children’s Hospitals Network, Westmead, NSW 2145, AustraliaMass gatherings are associated with the spread of communicable diseases. Some studies have suggested that acquisition of antimicrobial resistance (AMR) may be associated with attendance at specific mass gatherings. This systematic review aimed to synthesise evidence on the association between attendance at mass gatherings and antimicrobial resistance (AMR) and assess the prevalence of AMR at mass gatherings. A literature search of the Cochrane, Medline, Scopus, and Embase databases was performed. Studies were included if they reported original data, involved mass gatherings, and reported AMR results. Of 5559 titles screened, 44 studies met the inclusion criteria, most of which (<i>n</i> = 40) involved religious mass gatherings. The heterogeneity of the studies precluded a meta-analysis, hence a narrative synthesis by organism was conducted. A significant increase in antibiotic-resistant <i>Escherichia coli</i> and <i>Klebsiella pneumoniae</i> was reported following Hajj, as was a rise in gastrointestinal carriage of extended-spectrum β-lactamase (ESBL) or carbapenemase genes. Carriage of <i>Streptococcus pneumoniae</i> isolates non-susceptible to one or more antibiotics was also shown to increase from pre-Hajj to post-Hajj. There appears to be an association between attendance at mass gatherings and the acquisition of some AMR phenotypes and genotypes in some significant human pathogens, including <i>E. coli</i> and <i>S. pneumoniae</i>.https://www.mdpi.com/2414-6366/10/1/2antibioticsantimicrobial resistanceArbaeenHajjsystematic reviewmass gathering |
| spellingShingle | Linda Tong Pao Mohamed Tashani Catherine King Harunor Rashid Ameneh Khatami Antimicrobial Resistance Associated with Mass Gatherings: A Systematic Review Tropical Medicine and Infectious Disease antibiotics antimicrobial resistance Arbaeen Hajj systematic review mass gathering |
| title | Antimicrobial Resistance Associated with Mass Gatherings: A Systematic Review |
| title_full | Antimicrobial Resistance Associated with Mass Gatherings: A Systematic Review |
| title_fullStr | Antimicrobial Resistance Associated with Mass Gatherings: A Systematic Review |
| title_full_unstemmed | Antimicrobial Resistance Associated with Mass Gatherings: A Systematic Review |
| title_short | Antimicrobial Resistance Associated with Mass Gatherings: A Systematic Review |
| title_sort | antimicrobial resistance associated with mass gatherings a systematic review |
| topic | antibiotics antimicrobial resistance Arbaeen Hajj systematic review mass gathering |
| url | https://www.mdpi.com/2414-6366/10/1/2 |
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