The Phosphatase PHLPP2 Plays a Key Role in the Regulation of Pancreatic Beta-Cell Survival

Currently available antidiabetic treatments fail to halt, and may even exacerbate, pancreatic β-cell exhaustion, a key feature of type 2 diabetes pathogenesis; thus, strategies to prevent, or reverse, β-cell failure should be actively sought. The serine threonine kinase Akt has a key role in the reg...

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Bibliographic Details
Main Authors: Marta Letizia Hribal, Elettra Mancuso, Gaetano Paride Arcidiacono, Annalisa Greco, Donatella Musca, Teresa Procopio, Mariafrancesca Ruffo, Giorgio Sesti
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:International Journal of Endocrinology
Online Access:http://dx.doi.org/10.1155/2020/1027386
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