The value of revascularization and adherence to therapy in the development of cardiovascular complications in long-term monitoring of patients with myocardial infarction of the right ventricle on the background of the Q-myocardial infarction of the left ventricular posterior wall
The aim – to evaluate the role of deferred revascularization and adherence to drug therapy as factors affecting long-term prognosis of patients with myocardial infarction (MI) of the right ventricle (RV) on the background of the Q-myocardial infarction of the left ventricle (LV) posterior wall (PW)....
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TOV Chetverta Khvylia
2016-03-01
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| Series: | Кардіохірургія та інтервенційна кардіологія |
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| Online Access: | http://csic.com.ua/images/pdf/2016/1-2016/value-revascularization-adherence-therapy-development.pdf |
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| author | V.Y. Tseluyko T.A. Lozova V.P. Zheleznyy O.S. Sasyuk |
| author_facet | V.Y. Tseluyko T.A. Lozova V.P. Zheleznyy O.S. Sasyuk |
| author_sort | V.Y. Tseluyko |
| collection | DOAJ |
| description | The aim – to evaluate the role of deferred revascularization and adherence to drug therapy as factors affecting long-term prognosis of patients with myocardial infarction (MI) of the right ventricle (RV) on the background of the Q-myocardial infarction of the left ventricle (LV) posterior wall (PW).
Materials and methods. The study involved 155 patients with MI of the RV due the Q-MI of the PWLV, age 64.11 ± 0.78 years. The revascularization (PCI, CABG) was performed within one year after MI. Adherence to treatment was assessed after 6 and 30 months. The combined endpoints included: unstable angina (UA), Re-MI, stroke and cardio-vascular (CV) death. Follow-up was 30.6 ± 4.5 month.
Results. The 1st group included 68 (43.9 %) patients who underwent surgical treatment, 87 (56.1 %) patients under conservative strategy composed the 2nd group. The frequency of combined CV-point was significantly lower in the 1st group (ð = 0.00001). Revascularization after RV MI was accompanied by significant decrease of frequency of Re-MI (ð = 0.05), stroke (ð = 0.0413) and UA (ð = 0.00001) during 30 months follow-up. Reducing risk of CV events in the 1st group was associated with higher adherence to ACE inhibitors / ARA (86.7–79.4 %), statins (97.1–64.7 %) and clopidogrel (98.5–79.4 %) at 6 months and at the end of the observation period, compared to patients with conservative strategy (p < 0.05).
Conclusions. Higher adherence to drug therapy in the surgical treatment group is associated with significantly lower number of cardiovascular events during 30 days after right ventricular myocardial infarction. |
| format | Article |
| id | doaj-art-3250fa220a2e45beab083897d96bedc4 |
| institution | Kabale University |
| issn | 2305-3127 |
| language | English |
| publishDate | 2016-03-01 |
| publisher | TOV Chetverta Khvylia |
| record_format | Article |
| series | Кардіохірургія та інтервенційна кардіологія |
| spelling | doaj-art-3250fa220a2e45beab083897d96bedc42025-02-02T16:08:56ZengTOV Chetverta KhvyliaКардіохірургія та інтервенційна кардіологія2305-31272016-03-011 (12)1320The value of revascularization and adherence to therapy in the development of cardiovascular complications in long-term monitoring of patients with myocardial infarction of the right ventricle on the background of the Q-myocardial infarction of the left ventricular posterior wallV.Y. Tseluyko0T.A. Lozova1V.P. Zheleznyy2O.S. Sasyuk3Kharkiv Medical Academy of Postgraduate Education, UkraineSumy City Clinical Hospital N 1, UkraineSumy City Clinical Hospital N 1, UkraineSumy City Clinical Hospital N 1, UkraineThe aim – to evaluate the role of deferred revascularization and adherence to drug therapy as factors affecting long-term prognosis of patients with myocardial infarction (MI) of the right ventricle (RV) on the background of the Q-myocardial infarction of the left ventricle (LV) posterior wall (PW). Materials and methods. The study involved 155 patients with MI of the RV due the Q-MI of the PWLV, age 64.11 ± 0.78 years. The revascularization (PCI, CABG) was performed within one year after MI. Adherence to treatment was assessed after 6 and 30 months. The combined endpoints included: unstable angina (UA), Re-MI, stroke and cardio-vascular (CV) death. Follow-up was 30.6 ± 4.5 month. Results. The 1st group included 68 (43.9 %) patients who underwent surgical treatment, 87 (56.1 %) patients under conservative strategy composed the 2nd group. The frequency of combined CV-point was significantly lower in the 1st group (ð = 0.00001). Revascularization after RV MI was accompanied by significant decrease of frequency of Re-MI (ð = 0.05), stroke (ð = 0.0413) and UA (ð = 0.00001) during 30 months follow-up. Reducing risk of CV events in the 1st group was associated with higher adherence to ACE inhibitors / ARA (86.7–79.4 %), statins (97.1–64.7 %) and clopidogrel (98.5–79.4 %) at 6 months and at the end of the observation period, compared to patients with conservative strategy (p < 0.05). Conclusions. Higher adherence to drug therapy in the surgical treatment group is associated with significantly lower number of cardiovascular events during 30 days after right ventricular myocardial infarction.http://csic.com.ua/images/pdf/2016/1-2016/value-revascularization-adherence-therapy-development.pdfrevascularizationadherence to therapymyocardial infarction of the right ventriclecardiovascular complications |
| spellingShingle | V.Y. Tseluyko T.A. Lozova V.P. Zheleznyy O.S. Sasyuk The value of revascularization and adherence to therapy in the development of cardiovascular complications in long-term monitoring of patients with myocardial infarction of the right ventricle on the background of the Q-myocardial infarction of the left ventricular posterior wall Кардіохірургія та інтервенційна кардіологія revascularization adherence to therapy myocardial infarction of the right ventricle cardiovascular complications |
| title | The value of revascularization and adherence to therapy in the development of cardiovascular complications in long-term monitoring of patients with myocardial infarction of the right ventricle on the background of the Q-myocardial infarction of the left ventricular posterior wall |
| title_full | The value of revascularization and adherence to therapy in the development of cardiovascular complications in long-term monitoring of patients with myocardial infarction of the right ventricle on the background of the Q-myocardial infarction of the left ventricular posterior wall |
| title_fullStr | The value of revascularization and adherence to therapy in the development of cardiovascular complications in long-term monitoring of patients with myocardial infarction of the right ventricle on the background of the Q-myocardial infarction of the left ventricular posterior wall |
| title_full_unstemmed | The value of revascularization and adherence to therapy in the development of cardiovascular complications in long-term monitoring of patients with myocardial infarction of the right ventricle on the background of the Q-myocardial infarction of the left ventricular posterior wall |
| title_short | The value of revascularization and adherence to therapy in the development of cardiovascular complications in long-term monitoring of patients with myocardial infarction of the right ventricle on the background of the Q-myocardial infarction of the left ventricular posterior wall |
| title_sort | value of revascularization and adherence to therapy in the development of cardiovascular complications in long term monitoring of patients with myocardial infarction of the right ventricle on the background of the q myocardial infarction of the left ventricular posterior wall |
| topic | revascularization adherence to therapy myocardial infarction of the right ventricle cardiovascular complications |
| url | http://csic.com.ua/images/pdf/2016/1-2016/value-revascularization-adherence-therapy-development.pdf |
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