Extensive Morphea Following Adjuvant Radiotherapy for Breast Carcinoma—Case Report
Radiation-induced morphea (RIM) is a rare complication following radiotherapy (RT) for breast cancer treatment. Its distribution is usually confined to the breast having received radiotherapy. A generalized form of RIM also exists, defined as lesions extending beyond the radiotherapy site, but data...
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MDPI AG
2025-01-01
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| Series: | Current Oncology |
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| Online Access: | https://www.mdpi.com/1718-7729/32/1/50 |
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| author | Alexandru Panaitescu Hannah Nguyen Laurence Masson-Côté Carolina Lucena Fernandes |
| author_facet | Alexandru Panaitescu Hannah Nguyen Laurence Masson-Côté Carolina Lucena Fernandes |
| author_sort | Alexandru Panaitescu |
| collection | DOAJ |
| description | Radiation-induced morphea (RIM) is a rare complication following radiotherapy (RT) for breast cancer treatment. Its distribution is usually confined to the breast having received radiotherapy. A generalized form of RIM also exists, defined as lesions extending beyond the radiotherapy site, but data on the subject are scarce in the literature. This complication remains difficult to treat, due partly to the variable extent of disease and to individual clinical response rates to the wide array of available therapies, such as topical therapy (i.e., topical tacrolimus or topical corticosteroids), phototherapy, and systemic therapy (i.e., systemic immunosuppressants). We present a case of extensive morphea post RT for breast cancer with 2 years of favorable evolution under systemic therapy. |
| format | Article |
| id | doaj-art-323d19c7c85e4a5bbd52a499fa1a7649 |
| institution | Kabale University |
| issn | 1198-0052 1718-7729 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Current Oncology |
| spelling | doaj-art-323d19c7c85e4a5bbd52a499fa1a76492025-01-24T13:28:29ZengMDPI AGCurrent Oncology1198-00521718-77292025-01-013215010.3390/curroncol32010050Extensive Morphea Following Adjuvant Radiotherapy for Breast Carcinoma—Case ReportAlexandru Panaitescu0Hannah Nguyen1Laurence Masson-Côté2Carolina Lucena Fernandes3Radiation Oncology Service, Department of Nuclear Medicine and Radiation Oncology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC J1H 5N4, CanadaDermatology Service, Department of Medicine, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC J1H 5N4, CanadaRadiation Oncology Service, Department of Nuclear Medicine and Radiation Oncology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC J1H 5N4, CanadaDermatology Service, Department of Medicine, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC J1H 5N4, CanadaRadiation-induced morphea (RIM) is a rare complication following radiotherapy (RT) for breast cancer treatment. Its distribution is usually confined to the breast having received radiotherapy. A generalized form of RIM also exists, defined as lesions extending beyond the radiotherapy site, but data on the subject are scarce in the literature. This complication remains difficult to treat, due partly to the variable extent of disease and to individual clinical response rates to the wide array of available therapies, such as topical therapy (i.e., topical tacrolimus or topical corticosteroids), phototherapy, and systemic therapy (i.e., systemic immunosuppressants). We present a case of extensive morphea post RT for breast cancer with 2 years of favorable evolution under systemic therapy.https://www.mdpi.com/1718-7729/32/1/50radiation-induced morphealichen sclerosisKoebner phenomenonradiation therapybreast canceroncodermatology |
| spellingShingle | Alexandru Panaitescu Hannah Nguyen Laurence Masson-Côté Carolina Lucena Fernandes Extensive Morphea Following Adjuvant Radiotherapy for Breast Carcinoma—Case Report Current Oncology radiation-induced morphea lichen sclerosis Koebner phenomenon radiation therapy breast cancer oncodermatology |
| title | Extensive Morphea Following Adjuvant Radiotherapy for Breast Carcinoma—Case Report |
| title_full | Extensive Morphea Following Adjuvant Radiotherapy for Breast Carcinoma—Case Report |
| title_fullStr | Extensive Morphea Following Adjuvant Radiotherapy for Breast Carcinoma—Case Report |
| title_full_unstemmed | Extensive Morphea Following Adjuvant Radiotherapy for Breast Carcinoma—Case Report |
| title_short | Extensive Morphea Following Adjuvant Radiotherapy for Breast Carcinoma—Case Report |
| title_sort | extensive morphea following adjuvant radiotherapy for breast carcinoma case report |
| topic | radiation-induced morphea lichen sclerosis Koebner phenomenon radiation therapy breast cancer oncodermatology |
| url | https://www.mdpi.com/1718-7729/32/1/50 |
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